Results 21 to 30 of about 3,150,561 (392)
BMJ, 2005 Rectal artemether may be as good as intravenous quinine E very year over a million children die of malaria in Africa. In many settings, especially rural ones, most fatalities due to malaria occur outside hospital, although a substantial proportion of these children will have made contact with some level of healthcare in their final illness.1 Of those
Evelyn K. Ansah +2 more
openaire +4 more sources
BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA
Malang Neurology Journal, 2022 Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality.
Orlando Pikatan +3 more
doaj +1 more source
Plasmodium spp. mixed infection leading to severe malaria: a systematic review and meta-analysis
Scientific Reports, 2020 Mixed Plasmodium malaria infections can lead to severe malaria. This systematic review and meta-analysis aimed to explore the prevalence of severe mixed Plasmodium malaria infection and to compare it with the prevalence of severe P.
M. Kotepui +3 more
semanticscholar +1 more source
Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2023 Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver ...
Muhammad Vitanata Arfijanto +1 more
doaj +1 more source
Endothelial Activation, Acute Kidney Injury, and Cognitive Impairment in Pediatric Severe Malaria
Critical Care Medicine, 2020 Supplemental Digital Content is available in the text. Objectives: Evaluate the relationship between endothelial activation, malaria complications, and long-term cognitive outcomes in severe malaria survivors.
B. Ouma +11 more
semanticscholar +1 more source
NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients [PDF]
PeerJ, 2018 Background Host factors, including host genetic variation, have been shown to influence the outcome of Plasmodium falciparum infection. Genome-wide linkage studies have mapped mild malaria resistance genes on chromosome 6p21, whereas NCR3-412 ...
Alassane Thiam +12 more
doaj +2 more sources
Severe malaria: Biology, clinical manifestation, pathogenesis and consequences
Journal of Vector Borne Diseases, 2020 Every year, millions of people are infected with malaria, resulting in significant economic losses to the developing and developed nations. The malaria parasite pursues a complicated life cycle in an invertebrate, mosquito and vertebrate host with ...
V. Trivedi, SN Balaji, Rohitas Deshmukh
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The clinical presentation of Plasmodium falciparum malaria as severe versus uncomplicated is influenced by host genetic factors. Recently, a gain-of-function mutation in the mechanosensitive ion channel PIEZO1 was shown to protect mice ...
C. Nguetse +7 more
semanticscholar +1 more source
Severe childhood malaria syndromes defined by plasma proteome profiles [PDF]
, 2012 BACKGROUND Cerebral malaria (CM) and severe malarial anemia (SMA) are the most serious life-threatening clinical syndromes of Plasmodium falciparum infection in childhood.
A Hodgetts +36 more
core +9 more sources
eLife, 2021 Severe falciparum malaria has substantially affected human evolution. Genetic association studies of patients with clinically defined severe malaria and matched population controls have helped characterise human genetic susceptibility to severe malaria ...
James A Watson +20 more
doaj +1 more source