Artemether for severe malaria [PDF]
In 2011 the World Health Organization (WHO) recommended parenteral artesunate in preference to quinine as first-line treatment for people with severe malaria. Prior to this recommendation many countries, particularly in Africa, had begun to use artemether, an alternative artemisinin derivative.
Esu, Ekpereonne B +3 more
openaire +3 more sources
Severe vivax malaria in Eastern India
Background: Conventionally, vivax malaria was called as benign malaria. But recent reports of severe vivax malaria were coming from different parts of the World.
Joydeep Mukherjee
doaj +1 more source
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study [PDF]
Background: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum ...
Alexander, W Macharia +28 more
core +1 more source
Increased interferon-γ levels and risk of severe malaria: a meta-analysis
Interferon (IFN)-γ contributes to the pathogenesis of severe malaria; however, its mechanism remains unclear. Herein, differences in IFN-γ levels between patients with severe and uncomplicated malaria were evaluated using qualitative and quantitative ...
Aongart Mahittikorn +5 more
doaj +1 more source
Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]
Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund +2 more
core +2 more sources
RETRACTION: Top 100 cited articles on anosmia and COVID‐19: a bibliometric analysis
Retraction: Tan, DJY, Ko, TK. Top 100 cited articles on anosmia and COVID‐19: a bibliometric analysis. World J Otorhinolaryngol Head Neck Surg. 2023; 1–8. doi:10.1002/wjo2.125. The above article, published online on 28 July 2023 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor ...
Denise Jia Yun Tan, Tsz Ki Ko
wiley +1 more source
Determining the severity of Plasmodium falciparum malaria in Ethiopia
Summary: Background: In the majority of health centers in Ethiopia, the severity of falciparum malaria has been determined by parasitemia alone. However, it has been suggested that the use of peripheral infected RBC counts as an indicator of disease ...
Zinaye Tekeste +2 more
doaj +1 more source
Studies assessing the immunoglobulin G (IgG) antibody responses in severe malaria are not readily available. This study was designed to compare the IgG and IgG1-4 antibody responses in severe malaria and its major clinical presentations (cerebral ...
Tebit Emmanuel Kwenti +5 more
doaj +1 more source
Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study. [PDF]
BACKGROUND: Severe malaria may influence inner ear function, although this possibility has not been examined prospectively. In a retrospective analysis, hearing impairment was found in 9 of 23 patients with cerebral malaria.
A Freeland +53 more
core +1 more source
A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria [PDF]
Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of cells known as "rosettes." Despite a well documented association between rosetting and severe ...
A. O'Donnell +49 more
core +2 more sources

