Results 31 to 40 of about 235,333 (304)

Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial [PDF]

, 2016
This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design.
Milligan, Paul
core   +2 more sources

Approach to malaria in rural hospitals

CHRISMED Journal of Health and Research, 2014
Malaria is one of the most common parasitic infections in the developing countries. In Rural India, most patients would be treated by primary and secondary care physicians. This article is aimed at providing a feasible approach to the cases of malaria in
Jency Maria Koshy, Jacob Koshy, Vineeth Jaison, Preethi Paul   +3 more
doaj   +1 more source

Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets [PDF]

, 2018
Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to ...
A Bengtsson, A Claessens, A Djimde, A Salanti, A Salanti, BP Goncalves, C Lessa-Aquino, CI Newbold, CJ Treutiger, CW Wang, D Coulibaly, DH Davies, DI Baruch, F Lennartz, GI Bertin, GK Cham, GM Warimwe, HM Kyriacou, JA Chan, JA Chan, JD Smith, JT Griffin, K Marsh, KE Lyke, KE Lyke, L Turner, M Avril, M Fried, MA Travassos, MA Travassos, MJ Gardner, PD Crompton, RW Snow, S Gupta, SC Murphy, Severe falciparum malaria, SJ Rogerson, SS Oh, T Lavstsen, TE Taylor, TW Mwangi, XZ Su, Y Zhang   +42 more
core   +2 more sources

Alteration of Blood Lactate Levels in Severe Falciparum Malaria: A Systematic Review and Meta-Analysis

Biology, 2021
Metabolic acidosis in severe malaria usually occurs in the form of lactic acidosis. The present study aimed to collate articles from the literature that have reported blood lactate levels in patients with severe malaria and tested the hypothesis that ...
Polrat Wilairatana, Wanida Mala, Manas Kotepui, Kwuntida Uthaisar Kotepui   +3 more
doaj   +1 more source

The impact of low erythrocyte density in human blood on the fitness and energetic reserves of the African malaria vector Anopheles gambiae [PDF]

, 2013
Background Anaemia is a common health problem in the developing world. This condition is characterized by a reduction in erythrocyte density, primarily from malnutrition and/or infectious diseases such as malaria.
A Dao, A De Loof, A Rivero, AN Clements, B Schiefer, BA Okech, C Garrett-Jones, C Stone, D Proven, DE Impoinvil, E Van Handel, E Van Handel, E Van Handel, EO Lyimo, F Aboagye-Antwi, F Aboagye-Antwi, H Briegel, H Briegel, H Briegel, H Briegel, H Hurd, H Hurd, H Manda, Heather M Ferguson, HM Ferguson, II Abdelrahim, JC Beier, JC Hogg, JH Oliveira, JK Nayar, JM Mukiibi, JN Shieh, JR Carey, KA Carlson, LA Baton, Lisa C Ranford-Cartwright, M Bukar, MJ Crawley, NR Van den Broek, P Hougaard, PFL Boreham, PJ Taylor, PW Price, R Carter, R Ross, RA Anderson, RS Nasci, S Noushin Emami, SC Stearns, T Flatt, TK Nkuo-Akenji, TL Daniel, VF Fairbanks, WA Foster, WA Maier   +54 more
core   +3 more sources

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +3 more sources

Plasmodium falciparum infection patterns since birth and risk of severe malaria: a nested case-control study in children on the coast of Kenya. [PDF]

PLoS ONE, 2013
Children in malaria endemic areas acquire immunity to severe malaria faster than to mild malaria. Only a minority of children suffers from severe malaria and it is not known what determines this. The aim of this study was to establish how P.
Klara Lundblom, Linda Murungi, Victoria Nyaga, Daniel Olsson, Josea Rono, Faith Osier, Edna Ogada, Scott Montgomery, J Anthony G Scott, Kevin Marsh, Anna Färnert   +10 more
doaj   +1 more source

Clinical malaria case definition and malaria attributable fraction in the highlands of western Kenya. [PDF]

, 2014
BackgroundIn African highland areas where endemicity of malaria varies greatly according to altitude and topography, parasitaemia accompanied by fever may not be sufficient to define an episode of clinical malaria in endemic areas.
Afrane, Yaw A, Githeko, Andrew K, Yan, Guiyun, Zhou, Guofa   +3 more
core   +2 more sources

Clinical characteristics and outcome of severe malaria in Kapit, Sarawak, Malaysian Borneo

Journal of Vector Borne Diseases, 2023
Background & objectives: Severe malaria is a medical emergency and can lead to severe complications and death if not treated promptly and appropriately. Along with Plasmodium falciparum, P.
Chee Yik Chang
doaj   +1 more source

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]

, 2012
In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Amos, Ben, Chotivanich, Kesinee, Day, Nicholas P J, Dondorp, Arjen M, Fanello, Caterina I, Gesase, Samwel, Gomes, Ermelinda, Hendriksen, Ilse C E, Joseph, Sarah, Karema, Corine, Lee, Sue J, Maitland, Kathryn, Mtove, George, Mwanga-Amumpaire, Juliet, Olaosebikan, Rasaq, Pan-Ngum, Wirichada, Reyburn, Hugh, Saiwaew, Somporn, Silamut, Kamolrat, Tshefu, Antoinette K, von Seidlein, Lorenz, White, Lisa J, White, Nicholas J, Woodrow, Charles   +23 more
core   +5 more sources