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Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]
, 2012 Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund +2 more
core +2 more sources
The treatment of severe malaria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007 In the SEAQUAMAT trial, parenteral artesunate was shown to be associated with a considerably lower mortality than quinine, and is now the recommended treatment for severe malaria in low-transmission areas and in the second and third trimesters of pregnancy. A trial is underway to establish its role in African children.
Arjen M. Dondorp +3 more
openaire +4 more sources
Acidosis in severe childhood malaria [PDF]
QJM, 1997 Data were prospectively collected on 306 Kenyan children, including blood gases in 258 (75%). Severe malaria caused a predominantly high-anion-gap metabolic acidosis in at least 43% of children. Children with coma and respiratory distress (CM + RD) had greater evidence of renal dysfunction, lower mean pH and higher mean plasma osmolality than those ...
English, M. +6 more
openaire +6 more sources
Biology, 2021 Metabolic acidosis in severe malaria usually occurs in the form of lactic acidosis. The present study aimed to collate articles from the literature that have reported blood lactate levels in patients with severe malaria and tested the hypothesis that ...
Polrat Wilairatana +3 more
doaj +1 more source
Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]
, 2005 Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E +3 more
core +2 more sources
Lesson of the week: Assessing the severity of malaria [PDF]
BMJ, 2003 Life threatening malaria may develop even in patients who appear relatively well at ...
David Moore +6 more
openaire +3 more sources
Imported Plasmodium vivax malaria with severe thrombocytopaenia: can it be severe malaria or not? [PDF]
Malaria Journal, 2016 Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly mentioned as an indicator of P.
S. Antinori +6 more
openaire +4 more sources
Fluid therapy for severe malaria
The Lancet Infectious Diseases, 2022 Fluid therapy is an important supportive measure for patients with severe malaria. Patients with severe malaria usually have normal cardiac index, vascular resistance, and blood pressure and a small degree of hypovolaemia due to dehydration. Cell hypoxia, reduced kidney function, and acidosis result from microcirculatory compromise and malarial anaemia,
Kalkman, Laura C. +3 more
openaire +4 more sources
Approach to malaria in rural hospitals
CHRISMED Journal of Health and Research, 2014 Malaria is one of the most common parasitic infections in the developing countries. In Rural India, most patients would be treated by primary and secondary care physicians. This article is aimed at providing a feasible approach to the cases of malaria in
Jency Maria Koshy +3 more
doaj +1 more source
BMC Medicine, 2019 BackgroundAcute kidney injury (AKI) is a recognized complication of pediatric severe malaria, but its long-term consequences are unknown.MethodsUgandan children with cerebral malaria (CM, n = 260) and severe malaria anemia (SMA, n = 219) or community ...
A. Conroy +8 more
semanticscholar +1 more source