Results 41 to 50 of about 235,333 (304)

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis. [PDF]

, 2015
Inhibition of nitric oxide (NO) signaling may contribute to pathological activation of the vascular endothelium during severe malaria infection. Dimethylarginine dimethylaminohydrolase (DDAH) regulates endothelial NO synthesis by maintaining homeostasis ...
Ackerman, H, Alkaitis, MS, Billker, O, Casals-Pascual, C, Chertow, JH, Conway, DJ, Correa, S, Cunnington, AJ, Ebonyi, AO, Ikeda, AK, Jayasooriya, S, Nardone, G, Njie, M, Okebe, J, Walther, M   +14 more
core   +7 more sources

Severe and benign Plasmodium vivax malaria in Emberá (Amerindian) children and adolescents from an endemic municipality in Western Colombia

Journal of Infection and Public Health, 2016
Summary: Malaria in children is still an important public health problem in endemic areas of South-East Asia and Latin America. Certain forms of the disease, such as Plasmodium vivax severe malaria, are still neglected.
Diego A. Medina-Morales, Estefanía Montoya-Franco, Viviana d.P. Sanchez-Aristizabal, Jorge E. Machado-Alba, Alfonso J. Rodríguez-Morales   +4 more
doaj   +1 more source

Vitamin A Supplementation and Other Predictors of Anemia Among Children from Dar Es Salaam, Tanzania. [PDF]

, 2000
The associations of hemoglobin, hematocrit, and packed cell volume with socioeconomic factors, malaria, human immunodeficiency virus (HIV) infection, and nutritional status were examined among 687 children admitted to hospital with pneumonia ...
Fawzi, W W, Mbise, R, Ndossi, G, Spiegelman, D, Villamor, E   +4 more
core   +1 more source

Malaria: severe, life threatening. [PDF]

Clinical evidence, 2005
Severe malaria mainly affects children under 5 years old, non-immune travellers, migrants to malarial areas, and people living in areas with unstable or seasonal malaria. Cerebral malaria, causing encephalopathy and coma, is fatal in around 20% of children and adults, and neurological sequelae may occur in some survivors.
Omari, Aika, Garner, Paul
openaire   +4 more sources

Fluid therapy for severe malaria

The Lancet Infectious Diseases, 2022
Fluid therapy is an important supportive measure for patients with severe malaria. Patients with severe malaria usually have normal cardiac index, vascular resistance, and blood pressure and a small degree of hypovolaemia due to dehydration. Cell hypoxia, reduced kidney function, and acidosis result from microcirculatory compromise and malarial anaemia,
Kalkman, Laura C., Hanscheid, Thomas, Krishna, Sanjeev, Grobusch, Martin P.   +3 more
openaire   +4 more sources

Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia

BMJ Paediatrics Open
Background Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to
Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič   +12 more
doaj   +1 more source

A HOSPITAL-BASED RETROSPECTIVE COMPARATIVE STUDY OF COMPLICATIONS, OUTCOMES, CLINICAL AND LABORATORY PARAMETERS OF MALARIA WITH AND WITHOUT NEUROLOGICAL INVOLVEMENT

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Background & Objectives: Classically associated with Plasmodium falciparum, neurological complications in severe malaria is associated with increased morbidity and mortality.
Sohaib Ahmad, Nadia Shirazi, Nowneet Kumar Bhat, Minakshi Dhar, Garima Mittal, Manish Mittal, Nidhi Kaeley, Manoj Kumar   +7 more
doaj   +1 more source

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry, AA Semenya, AK Bei, Angela Siner, Atique M. Ahmed, B Singh, B Singh, Balbir Singh, BE Barber, BE Barber, C Aurrecoechea, C Daneshvar, Chan Woon Lu, CV Jennings, EV Meyer, G Butcher, G Snounou, H Ozwara, Ing Tien Wong, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Langhorne, J Li, J Rayner, Janet Cox-Singh, JC Barrett, JC Rayner, JC Rayner, JP Cramer, JW Barnwell, K Gunalan, K Hayton, Kenji Hirayama, KS Lee, L Excoffier, LH Bannister, LH Miller, LH Miller, M Willmann, MAM Sallum, Matthias Willmann, Miguel M. Pinheiro, MR Galinski, MR Galinski, N Gomez-Escobar, P Librado, Paul C. Divis, Ramlah Zainudin, RW Moon, S Kumar, S Lopaticki, S Nakazawa, Sanjeev Krishna, Sarina K. Singh-Khaira, Scott B. Millar, Sean Lynch, SL Takala, T William, TM DeSimone, WH Tham   +61 more
core   +3 more sources

Clinical factors for severity of Plasmodium falciparum malaria in hospitalized adults in Thailand. [PDF]

PLoS ONE, 2013
Plasmodium falciparum is a major cause of severe malaria in Southeast Asia, however, there is limited information regarding clinical factors associated with the severity of falciparum malaria from this region.
Patrick Sagaki, Vipa Thanachartwet, Varunee Desakorn, Duangjai Sahassananda, Supat Chamnanchanunt, Wirongrong Chierakul, Punnee Pitisuttithum, Prajej Ruangkanchanasetr   +7 more
doaj   +1 more source

Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

BMC Infectious Diseases, 2020
Background Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria.
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez, Frederick Ramirez Masangkay   +3 more
doaj   +1 more source