Results 61 to 70 of about 3,150,561 (392)

Severe imported malaria in a Serbian referral center [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. The World Health Organization estimates that 3.2 billion people are at a risk of being infected with malaria. Thus, the adequate diagnostic protocols for malaria, especially those aimed at determining disease severity, are paramount both ...
Poluga Jasmina, Karić Uroš, Dakić Zorica, Katanić Nataša, Lavadinović Lidija, Milošević Branko, Nikolić Nataša, Urošević Aleksandar, Jegorović Boris, Pavlović Milorad   +9 more
doaj   +1 more source

Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study [PDF]

, 2006
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by approximately 60 var genes per haploid genome.
Baea, Kay, Beck, Hans-Peter, Cockburn, Ian A, Cortés, Alfred, Kaestli, Mirjam, Rowe, J Alexandra   +5 more
core   +1 more source

Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

BMC Infectious Diseases, 2020
Background Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria.
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez, Frederick Ramirez Masangkay   +3 more
doaj   +1 more source

Clinical factors for severity of Plasmodium falciparum malaria in hospitalized adults in Thailand. [PDF]

PLoS ONE, 2013
Plasmodium falciparum is a major cause of severe malaria in Southeast Asia, however, there is limited information regarding clinical factors associated with the severity of falciparum malaria from this region.
Patrick Sagaki, Vipa Thanachartwet, Varunee Desakorn, Duangjai Sahassananda, Supat Chamnanchanunt, Wirongrong Chierakul, Punnee Pitisuttithum, Prajej Ruangkanchanasetr   +7 more
doaj   +1 more source

Plasma concentration of parasite DNA as a measure of disease severity in falciparum malaria. [PDF]

, 2014
In malaria-endemic areas, Plasmodium falciparum parasitemia is common in apparently healthy children and severe malaria is commonly misdiagnosed in patients with incidental parasitemia.
Chhaganlal, Kajal D, Day, Nicholas PJ, Dondorp, Arjen M, Faiz, M Abul, Gesase, Samwel, Hendriksen, Ilse CE, Imwong, Mallika, Mishra, Saroj, Mohanty, Sanjib, Mtove, George, Seni, Amir, Veenemans, Jacobien, Verhoef, Hans, White, Nicholas J, Woodrow, Charles J   +14 more
core   +1 more source

Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia

BMJ Paediatrics Open
Background Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to
Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič   +12 more
doaj   +1 more source

Clinical characteristics and outcome of severe malaria in Kapit, Sarawak, Malaysian Borneo

Journal of Vector Borne Diseases, 2023
Background & objectives: Severe malaria is a medical emergency and can lead to severe complications and death if not treated promptly and appropriately. Along with Plasmodium falciparum, P.
Chee Yik Chang
doaj   +1 more source

Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets [PDF]

, 2018
Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to ...
A Bengtsson, A Claessens, A Djimde, A Salanti, A Salanti, BP Goncalves, C Lessa-Aquino, CI Newbold, CJ Treutiger, CW Wang, D Coulibaly, DH Davies, DI Baruch, F Lennartz, GI Bertin, GK Cham, GM Warimwe, HM Kyriacou, JA Chan, JA Chan, JD Smith, JT Griffin, K Marsh, KE Lyke, KE Lyke, L Turner, M Avril, M Fried, MA Travassos, MA Travassos, MJ Gardner, PD Crompton, RW Snow, S Gupta, SC Murphy, Severe falciparum malaria, SJ Rogerson, SS Oh, T Lavstsen, TE Taylor, TW Mwangi, XZ Su, Y Zhang   +42 more
core   +2 more sources

Incidence and admission rates for severe malaria and their impact on mortality in Africa

Malaria Journal, 2017
Appropriate treatment of life-threatening Plasmodium falciparum malaria requires in-patient care. Although the proportion of severe cases accessing in-patient care in endemic settings strongly affects overall case fatality rates and thus disease burden ...
F. Camponovo, C. Bever, Katya Galactionova, Thomas A. Smith, M. Penny   +4 more
semanticscholar   +1 more source

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

Science Translational Medicine, 2017
Host and parasite RNA sequencing is combined with parasite load estimates to reveal mechanisms associated with human severe malaria. Uncomplicating malaria Plasmodium falciparum infections can progress to severe malaria, resulting in organ failure and ...
Hyun Jae Lee, Athina Georgiadou, M. Walther, D. Nwakanma, L. Stewart, M. Levin, T. Otto, D. Conway, L. Coin, A. Cunnington   +9 more
semanticscholar   +1 more source