Results 71 to 80 of about 3,150,561 (392)

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +3 more sources

Advocating an attack against severe malaria: a cost-effectiveness analysis

BMC Public Health, 2020
Background A recent study found that the gut microbiota, Lactobacillus and Bifidobacterium, have the ability to modulate the severity of malaria. The modulation of the severity of malaria is not however, the typical focal point of most widespread ...
Scott Greenhalgh, Veda Chandwani
doaj   +1 more source

Carriage of chloroquine-resistant parasites and delay of effective treatment increase the risk of severe malaria in Gambian children.

, 2005
Two hundred thirty-four Gambian children with severe falciparum malaria who were admitted to the pediatric ward of a rural district hospital each were matched for age with a same-sex control subject presenting as an outpatient with uncomplicated ...
Bousema, J Teun, Hallett, Rachel, Meerman, Larissa, Ord, Rosalynn, Osman, Emilia, Pinder, Margaret, Sutherland, Colin J, van Niekerk, Maarten, Walraven, Gijs   +8 more
core   +1 more source

Inter-Relationships of Cardinal Features and Outcomes of Symptomatic Pediatric Plasmodium falciparum Malaria in 1,933 Children in Kampala, Uganda [PDF]

, 2013
Malaria remains a challenging diagnosis with variable clinical presentation and a wide spectrum of disease severity. Using a structured case report form, we prospectively assessed 1,933 children at Mulago Hospital in Kampala, Uganda with acute Plasmodium
Cserti-Gazdewich, Christine M., Ddungu, Henry, Dhabangi, Aggrey, Dzik, Walter Henry, Mpimbaza, Arthur, Musoke, Charles, Nabukeera-Barungi, Nicolette, Nakiboneka-Ssenabulya, Deborah, Ssewanyana, Isaac   +8 more
core   +2 more sources

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria

Malaria Journal, 2018
Chitinase-3-like 1 (CHI3L1) is a glycoprotein elevated in paediatric severe malaria, and an emerging urinary biomarker of acute kidney injury (AKI). Based on the hypothesis that elevated CHI3L1 levels in malaria are associated with disease severity, the ...
A. Conroy, M. Hawkes, Robyn E. Elphinstone, R. Opoka, Sophie Namasopo, Chris C. Miller, C. John, K. Kain   +7 more
semanticscholar   +1 more source

Management of severe malaria [PDF]

Therapy, 2010
Plasmodium falciparum and other human malaria parasites can cause a variety of life-threatening syndromes. Diagnosis is difficult because none of these syndromes is unique to malaria, and parasitemia may be incidental rather than responsible for the illness. Malaria must be considered in the differential diagnosis of each of the severe syndromes it can
Macpherson Mallewa, Limangeni Mankhambo, Malcolm E. Molyneux, Ajib Phiri   +3 more
openaire   +2 more sources

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

Malaria Journal, 2011
Background Erythrocyte-associated antigenic polymorphisms or their absence have perhaps evolved in the human population to protect against malarial infection. Studies in various populations consistently demonstrate that blood group 'O' confers resistance
Tripathy Rina, Sahu Aditya N, Panda Santosh K, Panda Aditya K, Ravindran Balachandran, Das Bidyut K   +5 more
doaj   +1 more source

Assessment of perinatal outcomes of pregnant women with severe versus simple malaria.

PLoS ONE, 2021
ObjectiveMalaria in pregnancy is associated with adverse perinatal outcomes. The objective was to compare outcomes of simple and severe malaria and to determine whether they vary by trimester or severity of infection.MethodsProspective cohort study ...
Alfred Kwizera, Diomede Ntasumumuyange, Maria Small, Stephen Rulisa, Alexandra N Moscovitz, Urania Magriples   +5 more
doaj   +1 more source

The impact of low erythrocyte density in human blood on the fitness and energetic reserves of the African malaria vector Anopheles gambiae [PDF]

, 2013
Background Anaemia is a common health problem in the developing world. This condition is characterized by a reduction in erythrocyte density, primarily from malnutrition and/or infectious diseases such as malaria.
A Dao, A De Loof, A Rivero, AN Clements, B Schiefer, BA Okech, C Garrett-Jones, C Stone, D Proven, DE Impoinvil, E Van Handel, E Van Handel, E Van Handel, EO Lyimo, F Aboagye-Antwi, F Aboagye-Antwi, H Briegel, H Briegel, H Briegel, H Briegel, H Hurd, H Hurd, H Manda, Heather M Ferguson, HM Ferguson, II Abdelrahim, JC Beier, JC Hogg, JH Oliveira, JK Nayar, JM Mukiibi, JN Shieh, JR Carey, KA Carlson, LA Baton, Lisa C Ranford-Cartwright, M Bukar, MJ Crawley, NR Van den Broek, P Hougaard, PFL Boreham, PJ Taylor, PW Price, R Carter, R Ross, RA Anderson, RS Nasci, S Noushin Emami, SC Stearns, T Flatt, TK Nkuo-Akenji, TL Daniel, VF Fairbanks, WA Foster, WA Maier   +54 more
core   +3 more sources