Results 21 to 30 of about 855 (114)

Molecular Mechanisms of Frequency Discrimination in the Drosophila Ear

, 2022
Since the first confirmed evidence of potassium ions crossing the membrane to the first cloned and identified potassium channel from Drosophila melanogaster, the studies of potassium channels have extensively broadened our understanding of physiological ...
Zhang, Xiaowei
core   +1 more source

Pumilio binds para mRNA and requires nanos and brat to regulate sodium current in drosophila motoneurons [PDF]

, 2008
Homeostatic regulation of ionic currents is of paramount importance during periods of synaptic growth or remodeling. Our previous work has identified the translational repressor Pumilio (Pum) as a regulator of sodium current (INa) and excitability in ...
Moffat, K G, Weston, Andrew J., Baines, Richard A., Gerber, Andre P., Baines, R A, Muraro, Nara I., Luschnig, Stefan, Gerber, A P, Baines, Richard A.; id_orcid, Weston, A J, Moffat, Kevin G., Muraro, N I, Luschnig, S   +12 more
core   +1 more source

Dietary reference values for sodium

EFSA Journal, Volume 17, Issue 9, September 2019., 2019
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) derived dietary reference values (DRVs) for sodium. Evidence from balance studies on sodium and on the relationship between sodium intake and health outcomes, in particular cardiovascular disease (CVD)‐related endpoints and bone ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, John Kearney, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Peter Aggett, Susan Fairweather‐Tait, Ambroise Martin, Hildegard Przyrembel, Laura Ciccolallo, Agnès de Sesmaisons‐Lecarré, Silvia Valtueña Martinez, Laura Martino, Androniki Naska   +25 more
wiley   +1 more source

The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto‐Kakizaki Type 2 Diabetic Rat Heart

Journal of Diabetes Research, Volume 2018, Issue 1, 2018., 2018
Background. In vivo experiments in Goto‐Kakizaki (GK) type 2 diabetic rats have demonstrated reductions in heart rate from a young age. The expression of genes encoding more than 70 proteins that are associated with the generation and conduction of electrical activity in the GK sinoatrial node (SAN) have been evaluated to further clarify the molecular ...
F. C. Howarth, M. A. Qureshi, P. Jayaprakash, K. Parekh, M. Oz, H. Dobrzynski, T. E. Adrian, Michaelangela Barbieri   +7 more
wiley   +1 more source

Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells

Stem Cells International, Volume 2016, Issue 1, 2016., 2016
Msh homeobox 1 (MSX1) encodes a transcription factor implicated in embryonic development of limbs and craniofacial tissues including bone and teeth. Although MSX1 regulates osteoblast differentiation in the cranial bone of young animal, little is known about the contribution of MSX1 to the osteogenic potential of human cells.
Noriko Goto, Katsumi Fujimoto, Sakiko Fujii, Hiroko Ida-Yonemochi, Hayato Ohshima, Takeshi Kawamoto, Mitsuhide Noshiro, Chisa Shukunami, Katsuyuki Kozai, Yukio Kato, Gary E. Lyons   +10 more
wiley   +1 more source

Microarray‐Based Comparisons of Ion Channel Expression Patterns: Human Keratinocytes to Reprogrammed hiPSCs to Differentiated Neuronal and Cardiac Progeny

Stem Cells International, Volume 2013, Issue 1, 2013., 2013
Ion channels are involved in a large variety of cellular processes including stem cell differentiation. Numerous families of ion channels are present in the organism which can be distinguished by means of, for example, ion selectivity, gating mechanism, composition, or cell biological function.
Leonhard Linta, Marianne Stockmann, Qiong Lin, André Lechel, Christian Proepper, Tobias M. Boeckers, Alexander Kleger, Stefan Liebau, Michael Levin   +8 more
wiley   +1 more source

The Shaker Potassium Channel Is No Target for Xenon Anesthesia in Short‐Sleeping Drosophila melanogaster Mutants

The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
Background. Xenon seems to be an ideal anesthetic drug. To explore if next to the antagonism at the NMDA‐receptor other molecular targets are involved, we tested the xenon requirement in short sleeping Drosophila shaker mutants and in na[har38]. Methods.
C. Schaper, J. Höcker, R. Böhm, T. Roeder, B. Bein, Cyril Rivat, Art Zwerling   +6 more
wiley   +1 more source

Towards Therapeutic Applications of Arthropod Venom K+‐Channel Blockers in CNS Neurologic Diseases Involving Memory Acquisition and Storage

Journal of Toxicology, Volume 2012, Issue 1, 2012., 2012
Potassium channels are the most heterogeneous and widely distributed group of ion channels and play important functions in all cells, in both normal and pathological mechanisms, including learning and memory processes. Being fundamental for many diverse physiological processes, K+‐channels are recognized as potential therapeutic targets in the ...
Christiano D. C. Gati, Márcia R. Mortari, Elisabeth F. Schwartz, Yonghua Ji   +3 more
wiley   +1 more source

Recovery from slow inactivation in Shab channels

, 2016
Characterization of the voltage-dependent recovery of slow inactivation in Shab potassium ...
Leon Islas (3240087)
core   +1 more source

Structure and function of potassium and calcium channels [PDF]

, 2005
In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
core