Forming Next-Generation Antibody-Nanoparticle Conjugates through the Oriented Installation of Antibody Fragments [PDF]
, 2020 Use of antibody-nanoparticle conjugates (ANCs) has emerged as a multi-disciplinary strategy for combating cancer - they combine the versatility of nanoparticles and the potential to deliver cargo to cancer cells with the high targeting specificity of ...
Nogueira, João Carlos Faria
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Production Of Novel Recombinant Antipfhrp2 VNAR-G1 Protein Using Escherichia Coli Bl21(DE3) Expression System [PDF]
, 2020 Malaria rapid diagnostic tests (RDTs) act as important antibody-based immunoassays for prompt malaria diagnosis. Conventional monoclonal antibodies (mAbs) are widely used in RDTs but it can be easily degraded at high ambient temperatures.
Kok, Boon Hui
core
Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies [PDF]
, 2012 The immunoglobulin (Ig) protein domain is widespread in nature having a well-recognized role in proteins of the immune system. In this review, we describe the proteins containing Ig-like domains in Escherichia coli and entero-bacteria, reporting their ...
Bluhm, Hendrik +3 more
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Isolation And Characterization Of Shark Vnar Antibody Against Malaria Pfhrp2 Protein From Semi-Synthetic Library [PDF]
, 2019 Ujian diagnostik pantas (RDT) malaria adalah penguji imun berasaskan antibodi yang menpercepatkan diagnosis malaria. Walau bagaimanapun, reagen antibodi yang digunakan secara meluas untuk RDT malaria tertakluk kepada degradasi pada suhu sekitar yang ...
Cheong, Wei Shien
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, 2018 Additional file 1. PCR amplification of randomly selected plaques from the VNAR domains primary library using T7SelectUP (For) and T7SelectDOWN (Rev) sequencing primers. Lane M represents 100Â bp ladder; lane 1â 20 represents insert of single plaque; lane â ve represents negative control (PCR product with no cDNA template).
Chiuan Leow +4 more
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Beyond antibody engineering: directed evolution of alternative binding scaffolds and enzymes using yeast surface display [PDF]
Pioneered exactly 20 years ago, yeast surface display (YSD) continues to take a major role in protein engineering among the high-throughput display methodologies that have been developed to date. The classical yeast display technology relies on tethering
Kolmar, Harald, Könning, Doreen
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Next-Generation Antibody Therapeutics: Discovery, Development and Beyond: highlights of the third annual conference of the Chinese Antibody Society [PDF]
, 2019 The Chinese Antibody Society (CAS) convened the third annual conference in Cambridge, Massachusetts, USA on April 7, 2019. More than 600 global members attended the meeting.
Deng, M +4 more
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Anti-idiotype antibodies for biomedical applications [PDF]
Therapeutic antibodies have become an indispensable part of today's medicine. In addition to the implementation of antibodies in the treatment of a variety of different diseases, the most important area of application is cancer treatment.
Habermann, Jan
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Development Of Dengue Immunodiagnostic Assay By Targeting Denv Type 2 Ns1 Using Shark Single Domain Vnar Antibody [PDF]
Denv infection diagnosis requires early and rapid detection which is accurate and specific to provide effective treatment for the patients. However, problems such as limitations of rapid diagnostic test, antibody instability, cross-reaction among denv ...
Kok, Boon Hui
core
Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies [PDF]
The B-cell receptor (BCR) is a key player of the adaptive immune system. It is a unique part of immunoglobulin (Ig) molecules expressed on the surface of B cells. In case of many B-cell lymphomas, the tumor cells express a tumor-specific and functionally
Deweid, Lukas +8 more
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