Results 151 to 160 of about 79,021 (275)

Loss, persistence and reversal of phenotypic traits

Biological Reviews, Volume 101, Issue 5, Page 2119-2133, October 2026.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Purkinje cell arrival at the Purkinje cell layer orchestrates cerebellar foliation and its temporal sequence. [PDF]

iScience
Uchi R, Honda T, Kasai T, Hirota Y, Nakajima K.   +4 more
europepmc   +1 more source

Shh

netbib, 2001
openaire   +2 more sources

Opioid Allergy Registrations in Danish Electronic Health Records: A Multihospital Register‐Based Study With Journal Audit

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Accurate documentation of drug allergies is critical to prevent re‐exposure while avoiding unnecessary restrictions on safe pharmacotherapy. Although true opioid hypersensitivity is rare, adverse effects are frequently misclassified as allergies.
Andreas Halgreen Eiset, Signe Hertz Hansen, Sara Buttrup Rosenquist, Kenneth Skov, Lene Heise Garvey, Peter Gaarsdal Uhrbrand, Eva Aggerholm Sædder   +6 more
wiley   +1 more source

Sonic Hedgehog Signaling Promotes Survival and Lineage Specific Differentiation of Transplanted Neural Precursor Cells and Improves Motor Recovery After Thoracic Spinal Cord Injury in Rats. [PDF]

Biology (Basel)
Tail M, Zheng G, Zhang H, Wang H, Harms AK, Hatami M, Skutella T, Unterberg A, Zweckberger K, Younsi A.   +9 more
europepmc   +1 more source

Challenges in Diagnosing Central Adrenal Insufficiency in Children: Cortisol‐Stimulating Tests are Safe and Often Required

Clinical Endocrinology, Volume 105, Issue 4, Page 408-415, October 2026.
ABSTRACT Introduction The accuracy and safety of cortisol‐stimulating tests (CSTs) for assessing hypothalamic–pituitary–adrenal (HPA) axis integrity, including the diagnosis of central adrenal insufficiency (CAI), in children remain uncertain. Although these tests can simultaneously evaluate cortisol and growth hormone secretion, the present study ...
Mariana Peduti Halah, Ana Carolina Maia Teodózio, Davi Casale Aragon, Paula Conde Lamparelli Elias, Margaret de Castro, Ayrton Custodio Moreira, Sonir Rauber Antonini   +6 more
wiley   +1 more source

Medulloblastoma in concurrence with metastatic gastrointestinal stromal tumor: what's the GIST? Illustrative case. [PDF]

J Neurosurg Case Lessons
Leoni JA, Glasser JS, Hundley KN.
europepmc   +1 more source

Shh signaling in limb development

, 2013
Sonic hedgehog (Shh), a secreted signaling molecule, is generated from the posterior limb margin and essential in regulating anterior-posterior (A-P) patterning as well as growth and differentiation of limb mesenchyme.
Liu, Jiang
core  

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Mechanical Suppression of Sonic Hedgehog Signaling by Nucleus Pulposus Cells Underlies Early Disc Degeneration in Mouse. [PDF]

Cells
Virk S, Shah V, Piprode V, Kemp CM, Alluri H, Vincent KF, Krishnan R, Hong J, Albert TJ, Dahia CL.   +9 more
europepmc   +1 more source