Results 171 to 180 of about 79,021 (275)

Combining in vitro and in silico approaches to model neural tube patterning and isthmic organizer formation. [PDF]

NPJ Syst Biol Appl
Bertilsson F, Degener A, Ibek P, Rathore GS, Andersson E, Rifes P, Kirkeby A, Olariu V.   +7 more
europepmc   +1 more source

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1929-1941, September 2026.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

The tumor microenvironment of medulloblastoma: from emerging biological insights to novel therapeutic targeting. [PDF]

Front Oncol
Chien F, Michaud M, Stewart M, McThenia S, McSwain L, Tikunov A, Schniederjan MJ, Golde T, Gershon T, Bhasin M, MacDonald TJ.   +10 more
europepmc   +1 more source

Evidence for SHH as a candidate gene for encephalocele [PDF]

Clinical Dysmorphology, 2012
Kelly A, Bear, Benjamin D, Solomon, Erich, Roessler, Daniel E Pineda, Alvarez, Shobana, Kubendran, Margaret, O'Hara, Maximilian, Muenke   +6 more
openaire   +2 more sources

A Phase Ib Case Series Using Bortezomib With Chemotherapy in Atypical Teratoid/Rhabdoid Tumors

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Atypical teratoid/rhabdoid tumors (ATRTs) are aggressive pediatric brain tumors that are sensitive to proteasome inhibitors in preclinical models. We evaluated the feasibility of combining the proteasome inhibitor, bortezomib, with chemotherapy.
Wan‐Ling Ho, Ming‐Yun Hsieh, Yu‐Mei Liao, Shyh‐Shin Chiou, Her‐Shyong Shiah, Chang‐Hsu Chiang, Shiann‐Tarng Jou, Hsiu‐Ju Yen, Yi‐Yen Lee, Muh‐Lii Liang, Ting‐Chi Yeh, Yu‐Cheng Chou, Fang‐Liang Huang, Shu‐Huey Chen, Hsin‐Lun Lee, Chia‐Chun Kuo, Yi‐Shan Yang, Shu‐Mei Chen, Min‐Lan Tsai, Hsi Chang, Kevin Li‐Chun Hsieh, Chia‐Lang Fang, Chia‐Yau Chang, Jinn‐Li Wang, Chu‐Chin Chen, Joon‐Khim Loh, Pei‐Chin Lin, Tzu‐Chin Lin, Shih‐Chung Wang, Yi‐Fang Tu, Chao‐Neng Cheng, Jimmy Ming‐Jung Chuang, Huy Minh Tran, Shian‐Ying Sung, Irving Lai, Kuo‐Sheng Wu, James S. Miser, Yen‐Lin Liu, Tai‐Tong Wong   +38 more
wiley   +1 more source

Defective EV-mediated transport of SHH alters neural fate specification in EPM1 epilepsy. [PDF]

Sci Adv
Forero A, Pravata V, Pipicelli F, Frenna E, Soloperto A, Ianni M, Abate N, Di Matteo F, Bekjarova Z, Canafoglia L, Ragona F, Maccarrone G, Pisfil MG, Wahl-Schott C, Cernilogar FM, Eder M, Di Giaimo R, Cappello S.   +17 more
europepmc   +1 more source

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang, Shuwen Xue, Zhi Gao, Panlai Shi, Li Wang, Qi Feng, Xiangdong Kong, Xiaofan Zhu   +7 more
wiley   +1 more source

Hedgehog signaling enhances the Schwann-like and nerve repair-supportive properties of ectomesenchymal stem cells. [PDF]

Front Neurosci
Zhang D, Bian R, Ma Y, Yuan H, Wu X, Tang H, Zhao F.   +6 more
europepmc   +1 more source

Cannabidiol Ameliorates Blood–Brain Barrier Dysfunction and Inhibits Memory Astrocytes Activation in Mice With Sickness‐Like Behaviors

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Depressive‐like mice showed blood–brain barrier disruption with loss of endothelial tight junction proteins, astrocytic AQP4 depolarization, and elevated neuroinflammation. A single dose of cannabidiol restored BBB integrity and astrocyte polarity, suppressed memory astrocyte–mediated secondary neuroinflammation, and alleviated depressive‐like ...
Yue Chen, Hui Ma, Qian Long, Xuan Fang, Xiaotong Li, Wenhui Xiao, Xinzhou Deng, Fuze Du, Yifei Tan, Yan Wang, Xiaoxia Jiang, Bo Gao, Xin Qiao   +12 more
wiley   +1 more source

Pro-oncogenic immunohistochemical markers in Merkel cell carcinoma with or without polyomavirus signature: a Brazilian cohort. [PDF]

An Bras Dermatol
Talarico AS, de Oliveira Lima Carapeba M, de Souza CLF, Michalany AO, Jeunon de Sousa Vargas T, Engelman GG, Lellis RF, Stelini RF, Moraes JC, Caramella Pereira F, Gomes Moura IC, Gonçalves DC, Da Costa A.   +12 more
europepmc   +1 more source