Results 131 to 140 of about 74,513 (285)
Acta Neuropathologica CommunicationsSonic hedgehog subgroup of medulloblastoma (SHH-MB) is characterized by aberrant activation of the SHH signaling pathway. An inhibition of the positive SHH regulator Smoothened (SMO) has demonstrated promising clinical efficacy. Yet, primary and acquired
Foteini Tsiami +13 more
doaj +1 more source
SHH expression in human donor and cirrhotic liver.
, 2017 (A) Frozen (4 μm) human donor (n = 5), and cirrhotic liver sections [ALD (n = 6), NASH (n = 3), PBC (n = 1)] were screened for SHH (C-terminus) by immunofluorescence. 5x objective. Representative images shown.
David Geoffrey Bowen (3740554) +15 more
core +1 more source
Symbolic Interaction, EarlyView.This study of first‐year primary school draws on Goffman's concept of “collective behavior” to examine how order is established and disrupted through the mutual adjustment of all participants' actions. We employed a multi‐method longitudinal design, using semi‐standardized observations and qualitative interviews with teachers and children at three ...
Doris Bühler‐Niederberger +2 more
wiley +1 more source
, 2013 A: Expression of SHH, Gli1, Patched1, and E-cadherin mRNAs in the presence of L-Gli1i and SHH transduction. B: Western blot showing protein expression of Gli1, E-cadherin, and GAPDH in pancreatic cancer cell lines.
Huizhong Gan (311975) +13 more
core +1 more source
BJU International, Volume 135, Issue 4, Page 648-656, April 2025.Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong +14 more
wiley +1 more source
Caifeng Deng,1,* Si Zhang,2,* Chanyu Li,1 Zhiling Yang,1 Qin Guo,3 Yanmian Cheng4 1Department of Gynecology and Obstetrics, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People’s Republic of China ...
Deng C +5 more
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Nestin(+) cell-specific deletion of shh gene leads to more motor function deficits in shh iKO mice.
, 2015 I) strategy for nestin-expressing cell specific deletion of shh. II) in wt mice, shh expression is detected in many cells that are also nestin(+) in the SVZ (A) and in the ischemic site of the cortical stroke area (C). However, in shh iKO mice, only very
Nicholas C. Bambakidis (732637) +5 more
core +1 more source
BJU International, EarlyView.Objectives To examine the role of multiparametric magnetic resonance imaging (mpMRI) in enhancing prostate cancer (PCa) detection and selecting candidates for active surveillance (AS), given that its utility in monitoring disease progression remains unclear.
Seyed Hossein Hosseini Sharifi +19 more
wiley +1 more source
Brain Pathology, EarlyView.This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go +70 more
wiley +1 more source
Entwicklung der quergestreiften Ösophagusmuskulatur bei Shh-Mutantmäusen
, 2021 Objectives Sonic hedgehog (Shh) is a morphogen responsible for short- or long-term regulato-ry processes during embryonic development. Shh is expressed by the endodermal epithelium of the digestive and respiratory system, whereupon it is particularly ac ...
Beckmann, Julia
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