Results 111 to 120 of about 74,513 (285)

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah, Lessandra Y. S. Chee, Jie Su, Brian O'Sullivan, Christopher M. K. L. Yao, Enrique Sanz‐Garcia, Stephen M. Smith, Ilan Weinreb, Scott Bratman, B. C. John Cho, Ezra Hahn, Andrew Hope, Ali Hosni, John Kim, Andrew McPartlin, Nauman Malik, Chiaojung Jillian Tsai, John de Almeida, Anna Spreafico, Li Tong, Shao Hui Huang, John N Waldron   +21 more
wiley   +1 more source

Sonic hedgehog signaling in the development of the mouse hypothalamus

Frontiers in Neuroanatomy, 2015
The expression pattern of Sonic Hedgehog (Shh) in the developing hypothalamus changes over time. Shh is initially expressed in the prechordal mesoderm and later in the hypothalamic neuroepithelium-- first medially, and then in two off-medial domains ...
Sandra eBlaess, Nora eSzabo, Roberta eHaddad-Tóvolli, Xunlei eZhou, Gonzalo eAlvarez-Bolado   +4 more
doaj   +1 more source

Mapping the Shh regulatory landscape [PDF]

, 2015
Sonic hedgehog (Shh) is an important signalling protein expressed extensively in development, throughout tissues of the central nervous system, gut and the posterior of the limb bud. The complicated expression pattern of Shh is regulated by a series of
Anderson, Eve
core  

MCH expression is Shh dependent.

, 2013
(A, B) Photomicrographs to illustrate the aspect of a E17 Shh−/− embryo compared to a E17 wild type embryo. The mutant embryo is not viable due to multiple malformations in particular of the head. Scale bar: A = 1,5 mm; B = 4 mm.
Françoise Presse (337101), Jane Y. Wu (36803), Clotilde Amiot (337100), Xiaoping Chen (42085), Jean-Louis Nahon (250428), Sophie Croizier (337099), Dominique Fellmann (337102), Pierre-Yves Risold (337103)   +7 more
core   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Sewage Sludge and Cashew Bagasse Biochars Promote Changes in Selected Physical Attributes Related to the Structure of Degraded Dryland Soil

Journal of Plant Nutrition and Soil Science, EarlyView.
This study evaluated biochars from co‐pyrolysis of sewage sludge and cashew residues on physical quality of a degraded loamy sand soil. SPB applied at 20 Mg ha−1 reduced bulk density by 7.74%, whereas most porosity attributes were driven by soil reconsolidation rather than biochar. Aggregate stability varied with biochar type, with SPB promoting larger
João Marcos Rodrigues dos Santos, Ícaro Vasconcelos do Nascimento, Gilvanete da Silva Henrique, Tiago da Costa Dantas Moniz, Francisco Luan Almeida Barbosa, Alexandre dos Santos Queiroz, Adriana Guirado Artur, Mirian Cristina Gomes Costa, Helon Hébano de Freitas Sousa, Odair Pastor Ferreira, Laís Gomes Fregolente, Antônio Gomes de Souza Filho, Romildo Lopes de Oliveira Filho, Arthur Prudêncio de Araujo Pereira, Jaedson Cláudio Anunciato Mota   +14 more
wiley   +1 more source

Shh signaling pathway genes are expressed in SVZ NSCs.

, 2015
A.B.C) shh, smo, ptc expression in YFP (+) cells in the SVZ. D) shh expression in nestin(+) NSCs in SVZ. E). shh expression is detected in DCX+ neuroblasts in SVZ. H) shh expression in PCNA(+) cells. F.G) coexpression of shh with smo, and shh with ptc in
Nicholas C. Bambakidis (732637), Nataly Raviv (732635), Yongmin Jin (732634), Yu Luo (277978), Austin Barnett (732636), Emily Filichia (732638)   +5 more
core   +1 more source

Biochar‐Induced Shifts in Fungal Community Structure and Their Association With Soil Physical Properties in Degraded Soil From the Brazilian Semiarid

Land Degradation &Development, EarlyView.
ABSTRACT Soil degradation compromises ecosystem functioning. Biochar, a carbon‐rich amendment, has gained attention as a promising strategy to enhance soil structure and restore microbial balance. This study investigated the effects of two biochars, cashew bagasse biochar (CBB) and a co‐pyrolyzed biochar produced from sewage sludge and cashew pruning ...
João Marcos Rodrigues dos Santos, Arthur Prudêncio de Araujo Pereira, Kaio Gráculo Vieira Garcia, Ícaro Vasconcelos do Nascimento, Francisco Luan Almeida Barbosa, Tiago da Costa Dantas Moniz, Gilvanete da Silva Henrique, Murilo de Sousa Almeida, Vania Maria Maciel Melo, Mirian Cristina Gomes Costa, Helon Hébano de Freitas Sousa, Adriana Guirado Artur, Christiana de Fátima Bruce da Silva, Odair Pastor Ferreira, Antônio Gomes de Souza Filho, Erika Valente de Medeiros, Ademir Sergio Ferreira Araujo, Rafael Santiago da Costa, Jaedson Cláudio Anunciato Mota   +18 more
wiley   +1 more source

Changes in the number of CD31−CD45−Sca-1+ cells and Shh signaling pathway involvement in the lungs of mice with emphysema and relevant effects of acute adenovirus infection

, 2017
Minhua Deng,1,2 Jinhua Li,2 Ye Gan,3 Yan Chen,2 Ping Chen2 1Respiratory Medicine Department, PLA Rocket Force General Hospital, Beijing, 2Respiratory Medicine Department, 3Rehabilitation Department, Second Xiangya Hospital, Central South University ...
Chen P, Chen Y, Gan Y, Li JH, Deng MH
core  

Mechanisms of morphogen trafficking: Intraneuronal transport of Shh

, 2009
The Sonic hedgehog (Shh) morphogen plays an important role in shaping central nervous system (CNS) development. While the function of Shh signalling in many tissues is well understood, the intracellular regulation of Shh trafficking during these ...
Beug, Shawn Terrence
core   +1 more source