Results 81 to 90 of about 74,513 (285)
Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment
The Anatomical Record, EarlyView.Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga +4 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011 Background and Objectives: Recently, interest has increased in the potential employment of embryonic stem cells for the treatment of Parkinsonchr('39')s disease, which has been considered as an alternative therapeutic strategy.
H Niknejad +3 more
doaj
, 2013 The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk +5 more
core +1 more source
Shh mRNA expression in oligodendroglial cells.
, 2020 Multiplex in situ hybridization for Shh and for the oligodendroglial markers Olig2 and Sox10 as indicated, at the level of the tuberal region of the hypothalamus (Hpt) (A-B), the CA3 region of the hippocampus (C-D), the cerebral cortex (Ctx) (E-F), the ...
Mariagiovanna Russo (8474163) +5 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
PLoS ONE, 2013 Erectile dysfunction (ED) is a debilitating medical condition and current treatments are ineffective in patients with cavernous nerve (CN) injury, due to penile remodeling and apoptosis.
Nicholas L Angeloni +3 more
doaj +1 more source
NSCLC cells do not respond to exogenous Shh but can secrete Shh ligand.
, 2013 NSCLC cells were treated or not with recombinant Shh (500 ng/ml) at the indicated times. RT-qPCR was performed to evaluate Gli1 and Ptch1 mRNA levels upon treatment in A549 cells (A) and H520 cells (C).
Olga Bermudez (410727) +4 more
core +1 more source
Modern competency‐based teaching of human sexual development
Anatomical Sciences Education, EarlyView.Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler +2 more
wiley +1 more source
Expression of TGF and Shh Signaling Molecules after TGF-β or Shh Inhibition.
, 2013 (A) TGF-β signaling inhibitor, ALK5 kinase inhibitor, mitigated CsA-upregulated mRNA expression of Shh, Gli, and TGF-β by RT-PCR and protein expression Shh and TGF-β by Western blotting.
Yi Chung (547459), Earl Fu (583438)
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source