Results 111 to 120 of about 9,573 (184)

Exogenous trehalose improves the survival of date palm suckers by enhancing thioredoxin-antioxidant systems activity

Plant Stress
Trehalose, a disaccharide, regulates osmotic pressure, stabilizes proteins, and plays in the signaling of carbon allocation in response to abiotic stresses.
Majid Alikhani-Koupaei, Morteza Soleimani Aghdam   +1 more
doaj   +1 more source

Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments. [PDF]

J Comput Aided Mol Des, 2023
Freitas de Freitas T, Roth CD, Abbadi BL, Hopf FSM, Perelló MA, de Matos Czeczot A, de Souza EV, Borsoi AF, Machado P, Bizarro CV, Basso LA, Timmers LFSM.   +11 more
europepmc   +1 more source

Generation and Characterization of Stable Small Colony Variants of USA300 Staphylococcus aureus in RAW 264.7 Murine Macrophages

Antibiotics
Intracellular survival and immune evasion are typical features of staphylococcal infections. USA300 is a major clone of methicillin-resistant S. aureus (MRSA), a community- and hospital-acquired pathogen capable of disseminating throughout the body and ...
Dalida Bivona, Carmelo Bonomo, Lorenzo Colombini, Paolo G. Bonacci, Grete F. Privitera, Giuseppe Caruso, Filippo Caraci, Francesco Santoro, Nicolò Musso, Dafne Bongiorno, Francesco Iannelli, Stefania Stefani   +11 more
doaj   +1 more source

Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus

Synthetic and Systems Biotechnology, 2017
The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains ...
Eser Ünsaldı, Aslıhan Kurt-Kızıldoğan, Birgit Voigt, Dörte Becher, Gülay Özcengiz   +4 more
doaj   +1 more source

Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme

Organic Chemistry Frontiers, 2019
The rigidification of the high-energy conformation of shikimic acid was used to enhance inhibitor efficacy against shikimate kinase enzyme, an attractive target for antibiotic drug discovery.
Marina Pernas, Beatriz Blanco, Emilio Lence, Paul Thompson, Alastair R. Hawkins, Concepción González-Bello   +5 more
openaire   +4 more sources

A Virulence Factor from Sclerotinia sclerotiorum Targets the Host Chloroplast Proteins to Promote Infection

Plants
Chloroplasts are not only places for photosynthesis, but also participate in plant immunity and are important targets of pathogens. Pathogens secrete chloroplast-targeted proteins (CTPs) that disrupt host immunity and promote infection.
Wenjing Cui, Kunqin Xiao, Feng Yang, Kaibin Qiao, Xun Xu, Songyang Gu, Jinxin Guo, Zhuojian Song, Hongyu Pan, Fengting Wang, Yanhua Zhang, Jinliang Liu   +11 more
doaj   +1 more source

In-Depth Understanding of Cytoplasmic Male Sterility by Metabolomics in Spring Stem Mustard (Brassica juncea var. tumida Tsen et Lee)

Horticulturae
Male sterility (MS) caused by aborted pollen is a vital germplasm resource. In this study, metabolomic, transcriptomic, and proteomic analyses were performed to investigate the molecular regulatory mechanism of cytoplasmic male sterility (CMS) in the ...
Jie Wang, Ying Shen, Yunping Huang, Xiliang Ren, Tianyi Gao, Youjian Yu, Yuhong Wang, Qiufeng Meng   +7 more
doaj   +1 more source

GWAS Identifies SNP Markers and Candidate Genes for Off-Flavours and Protein Content in Faba Bean (Vicia faba L.)

Plants
Faba bean (Vicia faba L.) is a valuable ingredient in plant-based foods such as meat and dairy analogues. However, its typical taste and aroma are considered off-flavours in these food applications, representing a bottleneck during processing.
Antonio Lippolis, Boudewijn Hollebrands, Valentina Acierno, Catrienus de Jong, Laurice Pouvreau, João Paulo, Salvador A. Gezan, Luisa M. Trindade   +7 more
doaj   +1 more source

Synthesis of prenylquinones in chloroplasts [PDF]

, 1985
Bentley R., Block M. A., Boudet A. M., Buchholz B., Camara B., D. Schulze-Siebert, E. Fiedler, Fiedler E., G. Schultz, Goodwin T. W., Goodwin T. W., Heide L., Homeyer U., Inoue K., Interschick-Niebler E., J. Soll, Janiszowska W., Kosmac U., Leistner E., McKenna M., Nicholls D. G., Pennock J. F., Pennock J. F., Roughan P. G., Schultz G., Schultz G., Schultz G., Schulze-Siebert D., Soll J., Soll J., Spurgeon S. L., Stumpf P. K., Threlfall D. R., Whistance G. R., Williams M.   +34 more
core   +1 more source

Engineering cascade biocatalysis in whole cells for syringic acid bioproduction

Microbial Cell Factories
Background Syringic acid (SA) is a high-value natural compound with diverse biological activities and wide applications, commonly found in fruits, vegetables, and herbs.
Xin Liu, Yi An, Haijun Gao
doaj   +1 more source