Results 11 to 20 of about 552,514 (352)

Short-chain fatty acids in diseases

Cell Communication and Signaling, 2023
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1 and sodium ...
Dan Zhang, Yong-Ping Jian, Yu-Ning Zhang, Yao Li, Li-Ting Gu, Hui-Hui Sun, Ming-Di Liu, Hong-Lan Zhou, Yi-Shu Wang, Zhi-Xiang Xu   +9 more
doaj   +4 more sources

Short-chain fatty acids in nonalcoholic fatty liver disease: New prospects for short-chain fatty acids as therapeutic targets

Heliyon
Nonalcoholic fatty liver disease (NAFLD) is a stress-induced liver injury related to heredity, environmental exposure and the gut microbiome metabolism.
Xinyu Li, Maozhang He, Xinrui Yi, Xuejin Lu, Meizi Zhu, Min Xue, Yunshu Tang, Yaling Zhu   +7 more
doaj   +4 more sources

Short-chain fatty acids activate acetyltransferase p300 [PDF]

eLife, 2021
Short-chain fatty acids (SCFAs) acetate, propionate, and butyrate are produced in large quantities by the gut microbiome and contribute to a wide array of physiological processes. While the underlying mechanisms are largely unknown, many effects of SCFAs
Sydney P Thomas, John M Denu
doaj   +3 more sources

Occurrence and distribution of ladderane oxidation products in different oceanic regimes [PDF]

Biogeosciences, 2012
Ladderane fatty acids are commonly used as biomarkers for bacteria involved in anaerobic ammonium oxidation (anammox). These lipids have been experimentally shown to undergo aerobic microbial degradation to form short chain ladderane fatty acids. However,
D. Rush, E. C. Hopmans, S. G. Wakeham, S. Schouten, J. S. Sinninghe Damsté   +4 more
doaj   +5 more sources

Short-chain fatty acids in cancer pathogenesis

Cancer and Metastasis Reviews, 2023
Cancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents, mutations, diet, and environmental carcinogens.
M. Feitelson, A. Arzumanyan, Arvin Medhat, Ira Spector   +3 more
semanticscholar   +3 more sources

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production [PDF]

Nature Communications, 2017
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases ...
Jan Gajewski, Renata Pavlovic, Manuel Fischer, Eckhard Boles, Martin Grininger   +4 more
doaj   +5 more sources

Regulation of Inflammation by Short Chain Fatty Acids [PDF]

Nutrients, 2011
The short chain fatty acids (SCFAs) acetate (C2), propionate (C3) and butyrate (C4) are the main metabolic products of anaerobic bacteria fermentation in the intestine.
M. Vinolo, H. Rodrigues, R. Nachbar, R. Curi   +3 more
semanticscholar   +3 more sources

Reye's syndrome and short-chain fatty acids [PDF]

Neurology, 1985
Berlit, Peter, Bonjour, Jean-Pierre, Krause, Klaus-Henning   +2 more
core   +5 more sources

Role of short‐chain fatty acids in host physiology

Animal Models and Experimental Medicine
Short‐chain fatty acids (SCFAs) are major metabolites produced by the gut microbiota through the fermentation of dietary fiber, and they have garnered significant attention due to their close association with host health.
Mingyue Liu, Yubo Lu, Guoyu Xue, Le Han, Hanbing Jia, Zi Wang, Jia Zhang, Peng Liu, Chaojuan Yang, Yingjie Zhou   +9 more
doaj   +2 more sources

Distinct Effects of Short Chain Fatty Acids on Host Energy Balance and Fuel Homeostasis With Focus on Route of Administration and Host Species

Frontiers in Neuroscience, 2021
Accumulating evidence implicates gut-microbiota-derived metabolites as important regulators of host energy balance and fuel homeostasis, the underlying mechanisms are currently subject to intense research.
Dehuang Kong, Lidewij Schipper, Gertjan van Dijk   +2 more
doaj   +1 more source