Results 11 to 20 of about 405,625 (304)

The pharmacology and function of receptors for short-chain fatty acids [PDF]

Molecular Pharmacology, 2015
Despite some blockbuster G protein–coupled receptor (GPCR) drugs, only a small fraction (∼15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry.
Bolognini, Daniele, Milligan, Graeme, Moss, Catherine E., Tobin, Andrew B.   +3 more
core   +5 more sources

Short-chain fatty acids in nonalcoholic fatty liver disease: New prospects for short-chain fatty acids as therapeutic targets

Heliyon
Nonalcoholic fatty liver disease (NAFLD) is a stress-induced liver injury related to heredity, environmental exposure and the gut microbiome metabolism.
Xinyu Li, Maozhang He, Xinrui Yi, Xuejin Lu, Meizi Zhu, Min Xue, Yunshu Tang, Yaling Zhu   +7 more
doaj   +3 more sources

Reye's syndrome and short-chain fatty acids [PDF]

Neurology, 1985
Berlit, Peter, Bonjour, Jean-Pierre, Krause, Klaus-Henning   +2 more
core   +4 more sources

Short-chain fatty acids are potential goalkeepers of atherosclerosis

Frontiers in Pharmacology, 2023
Short-chain fatty acids (SCFAs) are metabolites produced by gut bacteria and play a crucial role in various inflammatory diseases. Increasing evidence suggests that SCFAs can improve the occurrence and progression of atherosclerosis.
Yu Feng, Danyan Xu
doaj   +3 more sources

Role of short‐chain fatty acids in host physiology

Animal Models and Experimental Medicine
Short‐chain fatty acids (SCFAs) are major metabolites produced by the gut microbiota through the fermentation of dietary fiber, and they have garnered significant attention due to their close association with host health.
Mingyue Liu, Yubo Lu, Guoyu Xue, Le Han, Hanbing Jia, Zi Wang, Jia Zhang, Peng Liu, Chaojuan Yang, Yingjie Zhou   +9 more
doaj   +3 more sources

Short-chain fatty acids [PDF]

, 2021
Global obesity rates are increasing more and more. Short-chain fatty acids, the end products of fermentation of indigestible carbohydrates by intestinal bacteria, can influence metabolism and therefore play a role in the development of obesity and diabetes.
openaire   +2 more sources

Effect of various dietary fats on fatty acid profile in duck liver: Efficient conversion of short-chain to long-chain omega-3 fatty acids [PDF]

, 2016
Citation: Chen, X., Du, X., Shen, J., Lu, L., & Wang, W. (2016). Effect of various dietary fats on fatty acid profile in duck liver: Efficient conversion of short-chain to long-chain omega-3 fatty acids.
Chen, Xi, Du, Xue, Lu, Lizhi, Shen, Jianliang, Wang, Weiqun   +4 more
core   +1 more source

Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function

Critical Care Explorations, 2021
Objectives:. The intestinal microbiome can modulate immune function through production of microbial-derived short-chain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty ...
Scott L. Weiss, MD, MSCE, Kyle Bittinger, PhD, Jung-Jin Lee, PhD, Elliot S. Friedman, PhD, Lisa M. Mattei, PhD, Kathryn Graham, BS, Donglan Zhang, BS, Jeny Bush, RNC, Fran Balamuth, MD, PhD, MSCE, Francis X. McGowan, Jr, MD, Frederic D. Bushman, PhD, Robert N. Baldassano, MD, Gary D. Wu, MD, Douglas C. Wallace, PhD, Ronald G. Collman, MD   +14 more
doaj   +1 more source

Short-Chain Fatty Acids [PDF]

, 2020
The relationship between diet and the diversity and function of the intestinal microbiomeand its importance for human health is currently the subject of many studies. The type and proportionof microorganisms found in the intestines can determine the energy balance of the host.
Paulina Markowiak-Kopeć, Katarzyna Śliżewska   +1 more
openaire   +1 more source

Short Chain Fatty Acids and Colon Cancer [PDF]

The Journal of Nutrition, 2002
The development of intestinal cancer involves complex genetic and epigenetic alterations in the intestinal mucosa. The principal signaling pathway responsible for the initiation of tumor formation, the APC-beta-catenin-TCF4 pathway, regulates both cell proliferation and colonic cell differentiation, but many other intrinsic and extrinsic signals also ...
Leonard H, Augenlicht, John M, Mariadason, Andrew, Wilson, Diego, Arango, WanCai, Yang, Barbara G, Heerdt, Anna, Velcich   +6 more
openaire   +2 more sources