Results 31 to 40 of about 197,415 (263)

Short-chain fatty acids as a link between diet and cardiometabolic risk: a narrative review

Lipids in Health and Disease, 2023
Aim Diet has a profound impact on cardiometabolic health outcomes such as obesity, blood glucose, blood lipids and blood pressure. In recent years, the gut microbiota has emerged as one of several potential key players explaining dietary effects on these
Eline Birkeland, Sedegheh Gharagozlian, Jørgen Valeur, Anne-Marie Aas   +3 more
doaj   +1 more source

Effect of Paclitaxel and Ferrostatin-1 administration on fecal short chain fatty acids

Revista Científica
Short-chain fatty acids are organic acids manufactured by the gut microbiota. The type and amount of microflora in the colon, the source of substrate and the transition period through the intestine affect the rate and amount of Short-chain fatty acids ...
Beyza Suvarikli-Alan, Zuhal Alkay, Göktuğ Şentürk, Avni Camgöz, Yunus Emre Tunçil, Tufan Keçeci, Feray Altan, Zafer Bulut   +7 more
doaj   +1 more source

Short-Chain and Unsaturated Fatty Acids Increase Sequentially From the Lag Phase During Cold Growth of Bacillus cereus

Frontiers in Microbiology, 2021
Fatty acids of two mesophilic and one psychrotrophic strains of the foodborne pathogen Bacillus cereus were analyzed by gas chromatography coupled to mass spectrometry during growth at cold (10 and 12°C) vs.
Marina Français, Romain Bott, Claire Dargaignaratz, Christian Giniès, Frédéric Carlin, Véronique Broussolle, Christophe Nguyen-Thé   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production

Nature Communications, 2017
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases ...
Jan Gajewski, Renata Pavlovic, Manuel Fischer, Eckhard Boles, Martin Grininger   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Potential Effects of Short-Chain Fatty Acids on the Epigenetic Regulation of Innate Immune Memory

Challenges, 2020
The regulation of innate immunity is substantially more ‘plastic’ than previously appreciated. Innate immune memory (manifested through trained immunity and tolerance) is a recently described epigenetic phenomenon that is a model example, with broad ...
Raphael Watt, Kimberley Parkin, David Martino   +2 more
doaj   +1 more source

Supplementation of lactic acid bacteria has positive effects on the mucosal health of Atlantic salmon (Salmo salar) fed soybean meal

Aquaculture Reports, 2023
We investigated the ability of lactic acid bacteria, when added individually or in combination in feeds, to prevent soybean meal-induced enteritis in Atlantic salmon.
Nadanasabesan Nimalan, Solveig Lysfjord Sørensen, Adriána Fečkaninová, Jana Koščová, Dagmar Mudroňová, Soňa Gancarčíková, Ioannis N. Vatsos, Saraswathy Bisa, Viswanath Kiron, Mette Sørensen   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source