Results 21 to 30 of about 547,631 (352)

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

Journal of Lipid Research, 2013
Short-chain fatty acids (SCFAs), the end products of fermentation of dietary fibers by the anaerobic intestinal microbiota, have been shown to exert multiple beneficial effects on mammalian energy metabolism.
G. den Besten, K. van Eunen, A. Groen, K. Venema, D. Reijngoud, Barbara M. Bakker   +5 more
semanticscholar   +1 more source

Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis

International Journal of Molecular Sciences, 2022
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with the host, and related metabolites have profound effects on human health ...
P. Portincasa, L. Bonfrate, M. Vacca, M. De Angelis, Ilaria Farella, Elisa Lanza, M. Khalil, D. Q. Wang, M. Sperandio, A. Di Ciaula   +9 more
semanticscholar   +1 more source

A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias [PDF]

, 2017
Free Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the lower gut by microbial fermentation of non-digestible carbohydrates.
Aoki, Junken, Bolognini, Daniele, Hansen, Anders Højgaard, Hudson, Brian D., Inoue, Asuka, Kawakami, Kouki, Kishi, Takayuki, Milligan, Graeme, Sergeev, Eugenia, Ulven, Trond   +9 more
core   +3 more sources

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

Frontiers in Immunology, 2019
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial and environmental factors.
Daniela Parada Venegas, M. De la Fuente, G. Landskron, María-Julieta González, R. Quera, G. Dijkstra, H. Harmsen, K. Faber, M. Hermoso   +8 more
semanticscholar   +1 more source

Treatment of type 2 diabetes by free fatty acid receptor agonists [PDF]

, 2014
Dietary free fatty acids (FFAs), such as ω-3 fatty acids, regulate metabolic and anti-inflammatory processes, with many of these effects attributed to FFAs interacting with a family of G protein-coupled receptors.
Hudson, Brian D., Milligan, Graeme, Ulven, Trond, Watterson, Kenneth R.   +3 more
core   +2 more sources

Analysis on the Difference of Flavor Precursors of Daqingshan Goat Meat in Different Feeding Environments, Ages and Cuts

Shipin gongye ke-ji, 2022
Objective: Exploring the variation law of flavor precursors in Daqing goat meat, this paper provided a basis for the in-depth study of meat quality and flavor characteristics. Methods: The changes rule of meat flavor precursors, reducing sugar, thiamine,
Baojun ZHANG, Meiling GE, Zhihong LIU, Yanjun ZHANG, Jinquan LI, Yinfeng HE   +5 more
doaj   +1 more source

The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health

Gut microbes, 2021
The gut microbiota plays an important role in cardio-metabolic diseases with diet being among the strongest modulators of gut microbiota composition and function. Resistant dietary carbohydrates are fermented to short-chain fatty acids (SCFAs) by the gut
A. Nogal, A. Valdes, C. Menni
semanticscholar   +1 more source

Regulation of short-chain fatty acid production [PDF]

Proceedings of the Nutrition Society, 2003
Short-chain fatty acid (SCFA) formation by intestinal bacteria is regulated by many different host, environmental, dietary and microbiological factors. In broad terms, however, substrate availability, bacterial species composition of the microbiota and intestinal transit time largely determine the amounts and types of SCFA that are produced in healthy ...
Sandra, Macfarlane, George T, Macfarlane
openaire   +2 more sources

Effect of various dietary fats on fatty acid profile in duck liver: Efficient conversion of short-chain to long-chain omega-3 fatty acids [PDF]

, 2016
Citation: Chen, X., Du, X., Shen, J., Lu, L., & Wang, W. (2016). Effect of various dietary fats on fatty acid profile in duck liver: Efficient conversion of short-chain to long-chain omega-3 fatty acids.
Chen, Xi, Du, Xue, Lu, Lizhi, Shen, Jianliang, Wang, Weiqun   +4 more
core   +1 more source

The pharmacology and function of receptors for short-chain fatty acids [PDF]

, 2015
Despite some blockbuster G protein–coupled receptor (GPCR) drugs, only a small fraction (∼15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry.
Bolognini, Daniele, Milligan, Graeme, Moss, Catherine E., Tobin, Andrew B.   +3 more
core   +1 more source