Results 11 to 20 of about 234,936 (321)

Relatively semi-conservative replication and a folded slippage model for short tandem repeats

BMC Genomics, 2020
Background The ubiquitous presence of short tandem repeats (STRs) in virtually all genomes implicates their functional relevance, while a widely-accepted definition of STR is yet to be established. Previous studies majorly focus on relatively longer STRs,
Hongxi Zhang, Douyue Li, Xiangyan Zhao, Saichao Pan, Xiaolong Wu, Shan Peng, Hanrou Huang, Ruixue Shi, Zhongyang Tan   +8 more
doaj   +2 more sources

Forensic Autosomal Short Tandem Repeats and Their Potential Association With Phenotype

Frontiers in Genetics, 2020
Forensic DNA profiling utilizes autosomal short tandem repeat (STR) markers to establish identity of missing persons, confirm familial relations, and link persons of interest to crime scenes.
Nicole Wyner, Mark Barash, Mark Barash, Dennis McNevin   +3 more
doaj   +2 more sources

The repertoire of short tandem repeats across the tree of life [PDF]

Genome Biology
Background Short tandem repeats (STRs) are widespread, dynamic repetitive elements with a number of biological functions and relevance to human diseases, genome plasticity and adaptation. However, their prevalence across taxa remains poorly characterized.
Nikol Chantzi, Ilias Georgakopoulos-Soares   +1 more
doaj   +2 more sources

Evaluation of genetic instability of short tandem repeats in hepatocellular carcinoma [PDF]

Scientific Reports
Hepatocellular carcinoma (HCC) ranked as the sixth most common malignancy and the third leading cause of cancer-related mortality with approximately 830, 000 deaths worldwide annually.
Yinghui Song, Ming Xu, Yufeng Li, Xinling Zhang, Wei Xu   +4 more
doaj   +2 more sources

Mutations of short tandem repeats explain abundant trait heritability in Arabidopsis [PDF]

Genome Biology
Background Short tandem repeat (STR) mutations are major drivers of genetic variation and deeply influence phenotypic diversity and evolution, they are often overlooked despite their significant effects.
Zhi-Qin Zhang, Juan Jiang, Yong-Chao Xu, Craig Dent, Sridevi Sureshkumar, Sureshkumar Balasubramanian, Ya-Long Guo   +6 more
doaj   +2 more sources

Genotyping short tandem repeats across copy number alterations, aneuploidies, and polyploid organisms [PDF]

Communications Biology
Short tandem repeats (STRs) are a rich source of genetic variation, but are difficult to genotype. While specialized repeat variant callers exist, they typically assume a euploid human genome.
Max A. Verbiest, Elena Grassi, Andrea Bertotti, Maria Anisimova   +3 more
doaj   +3 more sources

Link between short tandem repeats and translation initiation site selection

Human Genomics, 2018
Background Despite their vast biological implication, the relevance of short tandem repeats (STRs)/microsatellites to the protein-coding gene translation initiation sites (TISs) remains largely unknown.
Masoud Arabfard, Kaveh Kavousi, Ahmad Delbari, Mina Ohadi   +3 more
doaj   +2 more sources

Natural variation in C. elegans short tandem repeats. [PDF]

Genome Res, 2022
Short tandem repeats (STRs) represent an important class of genetic variation that can contribute to phenotypic differences. Although millions of single nucleotide variants (SNVs) and short indels have been identified among wild Caenorhabditis elegans strains, the natural diversity in STRs ...
Zhang G, Wang Y, Andersen EC.
europepmc   +3 more sources

Polymorphic short tandem repeats make widespread contributions to blood and serum traits. [PDF]

Cell Genom, 2023
Margoliash J, Fuchs S, Li Y, Zhang X, Massarat A, Goren A, Gymrek M.   +6 more
europepmc   +2 more sources

STRScan: targeted profiling of short tandem repeats in whole-genome sequencing data

BMC Bioinformatics, 2017
Background Short tandem repeats (STRs) are found in many prokaryotic and eukaryotic genomes, and are commonly used as genetic markers, in particular for identity and parental testing in DNA forensics.
Haixu Tang, Etienne Nzabarushimana
doaj   +2 more sources