Results 51 to 60 of about 234,936 (321)
Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex
Cell Reports, 2016 Summary: Tandem repetitive DNA is highly abundant in eukaryotic genomes and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown.
Haijin He +4 more
doaj +1 more source
Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing
Frontiers in Genetics, 2022 Background: Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple genetic diseases and the regulation of gene expression. Long-read sequencing (LRS) offers a potential solution to genome-wide STR analysis. However,
Zhenhua Liu +33 more
doaj +1 more source
Urological Science, 2023 Purpose: The purpose of this study was to demonstrate the usefulness of genetic analysis with short tandem repeats (STRs) to identify the cellular origin of an unusual allograft urothelial carcinoma (UC).
Jia-Yuh Sheu +4 more
doaj +1 more source
The challenge of small-scale repeats for indel discovery
Frontiers in Bioengineering and Biotechnology, 2015 Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj +1 more source
Inferring short tandem repeat variation from paired-end short reads [PDF]
Nucleic Acids Research, 2013 The advances of high-throughput sequencing offer an unprecedented opportunity to study genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive DNA regions. We present a Bayesian method to estimate repeat-length variation from paired-end sequence read data.
Cao, Minh Duc +7 more
openaire +3 more sources
Discriminatory ability of hypervariable variable number tandem repeat loci in population-based analysis of Mycobacterium tuberculosis strains, London, UK [PDF]
, 2009 To address conflicting results about the stability of variable number tandem repeat (VNTR) loci and their value in prospective molecular epidemiology of Mycobacterium tuberculosis, we conducted a large prospective population-based analysis of all M ...
Brown, T +3 more
core +3 more sources
Short Tandem Repeats (STR) in cattle genomics and breeding [PDF]
Biotechnology in Animal Husbandry, 2018 Molecular markers are essential tool for determining the specific genetic makeup of an individual and are valuable approach for genetic improvement of farm animals.
Teneva Atanaska +7 more
doaj
Landscape of standing variation for tandem duplications in Drosophila yakuba and Drosophila simulans [PDF]
, 2014 We have used whole genome paired-end Illumina sequence data to identify tandem duplications in 20 isofemale lines of D. yakuba, and 20 isofemale lines of D. simulans and performed genome wide validation with PacBio long molecule sequencing. We identify 1,
Andolfatto, Peter +5 more
core +3 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Frontiers in Genetics, 2021 The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China.
Chong Chen +18 more
doaj +1 more source