Results 61 to 70 of about 234,936 (321)

Development of Multi-Locus Variable Number Tandem Repeat Analysis for Outbreak Detection of Neisseria meningitidis [PDF]

, 2006
Neisseria meningitidis is a major cause of septicemia and meningitis worldwide. Traditional typing methods like pulsed-field gel electrophoresis (PFGE) for identifying outbreaks are subjective and time consuming.
Price, Alicia Anne
core  

Multiple Locus Variable number of tandem repeat Analysis : a molecular genotyping tool for Paenibacillus larvae [PDF]

, 2016
American Foulbrood, caused by Paenibacillus larvae, is the most severe bacterial disease of honey bees (Apis mellifera). To perform genotyping of P.larvae in an epidemiological context, there is a need of a fast and cheap method with a high resolution ...
Alippi, Alippi, Antunez, Ash, Ash, Bassi, Belkum, Belkum, Buhlmann, Bui, Chan, Djordjevic, Djukic, Dobbelaere, Gelfand, Genersch, Genersch, Genersch, Genersch, Girard, Graaf, Graaf, Heyndrickx, Katznelson, Klevytska, Lindstedt, Lindstrom, Lindstrom, Loncaric, Malachowa, Mazars, Morrissey, Neuendorf, Qin, Schafer, Stratilo, Techaruvichit, Torres-Cruz, U'Ren, Vogler, Wu   +40 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats

bioRxiv, 2019
Structural variants (SVs) and short tandem repeats (STRs) are important sources of genetic diversity but are not routinely analyzed in genetic studies because they are difficult to accurately identify and genotype.
David A. Jakubosky, Erin N. Smith, M. D’Antonio, M. Bonder, William W. Greenwald, Agnieszka D’Antonio-Chronowska, H. Matsui, O. Stegle, S. Montgomery, Christopher M. DeBoever, K. Frazer   +10 more
semanticscholar   +1 more source

Measuring microsatellite conservation in mammalian evolution with a phylogenetic birth-death model. [PDF]

, 2012
Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection.
Buschiazzo, Emmanuel, Gemmell, Neil, Lennon, Dustin, Minin, Vladimir N, Sawaya, Sterling M   +4 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Short tandem repeats genotyping of gestational choriocarcinoma – our experiences

Taiwanese Journal of Obstetrics & Gynecology
Objective: This short communication demonstrates how short tandem repeat genotyping can identify the origin of gestational choriocarcinoma. Materials and methods: The origin of gestational choriocarcinoma in our three cases was determined using the short
Lajos Gergely, Vanda Repiska, Robert Petrovic, Miroslav Korbel, Ludovit Danihel, Jozef Sufliarsky, Michaela Kubickova, Helena Gbelcova, Petra Priscakova   +8 more
doaj   +1 more source

Microsatellite Stability in STR Analysis Aspergillus fumigatus Depends on Number of Repeat Units

Frontiers in Cellular and Infection Microbiology, 2019
More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers.
Theun de Groot, Jacques F. Meis, Jacques F. Meis, Jacques F. Meis   +3 more
doaj   +1 more source

Tandem repeat finding in DNA using nucleotide density vectors [PDF]

, 2014
Tato práce se zabývá výskytem tandemových repetic v makromolekule DNA a možnostmi jejich vyhledávání v genomu. Součástí této bakalářské práce je krátké seznámení se strukturou DNA, popis tandemových repetic a jejich definice, členění a jejich vliv a ...
Hracho, Michal
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source