Results 81 to 90 of about 5,135,061 (391)

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

A study to assess serum and tissue levels of sialic acid and hexosamine in keloids

open access: yesMRIMS Journal of Health Sciences, 2015
Background: A keloid is an abnormal proliferation of scar tissue that forms at the site of cutaneous injury. The major component of scar tissue is the fibrous protein collagen, which is a glycoprotein.
M Girija Menon   +3 more
doaj   +1 more source

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. [PDF]

open access: yes, 2018
Anti-carbohydrate monoclonal antibodies (mAbs) hold great promise as cancer therapeutics and diagnostics. However, their specificity can be mixed, and detailed characterization is problematic, because antibody-glycan complexes are challenging to ...
Amon, Ron   +12 more
core   +2 more sources

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Evaluation of salivary sialic acid and salivary Alpha-L-Fucosidase levels in patients with oral submucous fibrosis- A cross-sectional study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Saliva, a non-invasive diagnostic tool, is used to evaluate sialic acid and Alpha-L-Fucosidase in OSMF. Sialylation and fucosylation are glycosylation changes that mediate vital biological functions.
Sunaina Swatantramath   +4 more
doaj   +1 more source

DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety [PDF]

open access: yes, 1991
We have previously demonstrated that transferrin-polycation conjugates are efficient carrier molecules for the introduction of genes into eucariotic cells.
Birnstiel, Max L.   +4 more
core   +1 more source

Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing

open access: yesAdvanced Materials, EarlyView.
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko   +2 more
wiley   +1 more source

Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

open access: yesNature Communications, 2023
Staphylococcus aureus is a predominant cause of chronic lung infections. While the airway environment is rich in highly sialylated mucins, the interaction of S. aureus with sialic acid is poorly characterized. Using S.
Xiongqi Ding   +21 more
doaj   +1 more source

Efficient TurboID-based proximity labelling method for identifying terminal sialic acid glycosylation in living cells

open access: yesActa Biochimica et Biophysica Sinica, 2022
TurboID, a proximity labelling method based on mutant biotin ligase, is an efficient new technique for recognizing protein-protein interactions and has been successfully applied to living cells.
Liu Wu   +7 more
doaj   +1 more source

Spatiotemporal expression patterns of sialoglycoconjugates during nephron morphogenesis and their regional and cell type-specific distribution in adult rat kidney [PDF]

open access: yes, 2018
The expression of α2,6- and α2,3-linked sialic acids on N-glycans was studied in embryonic, postnatal, and adult rat kidney. Histochemistry and blotting using Polyporus squamosus and Sambucus nigra lectins for α2,6-linked sialic acids and the Maackia ...
Goldstein, Irwin   +5 more
core  

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