Results 11 to 20 of about 11,605 (209)
A new assay for determining ganglioside sialyltransferase activities lactosylceramide-2,3-sialyltransferase (SAT I) and monosialylganglioside-2,3-sialyltransferase (SAT IV). [PDF]
PLoS ONE, 2014 A new assay for the determination of lactosylceramide-2,3-sialyltransferase (SAT I, EC 2.4.99.9) and monosialoganglioside sialyltransferase (SAT IV, EC 2.4.99.2) is described.
Cynthia Q Sun +4 more
doaj +2 more sources
Marine Bacterial Sialyltransferases [PDF]
Marine Drugs, 2010 Sialyltransferases transfer N-acetylneuraminic acid (Neu5Ac) from the common donor substrate of these enzymes, cytidine 5’-monophospho-N-acetylneuraminic acid (CMP-Neu5Ac), to acceptor substrates.
Takeshi Yamamoto
doaj +3 more sources
Sialyltransferase inhibition and recent advances [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2016 Sialic acids, existing as terminal sugars of glycoconjugates, play important roles in various physiological and pathological processes, such as cell-cell adhesion, immune defense, tumor cell metastasis, and inflammation. Sialyltransferases (STs) catalyze the transfer of sialic acid residues to non-reducing oligosaccharide chains of proteins and lipids,
Libo, Wang +3 more
openaire +4 more sources
Cystic fibrosis liver sialyltransferase
Clinical Genetics, 1978 The activity of sialyltransferase with regard to the glycoprotein substrates asialofetuin and asialo‐ovine submaxillary mucin was determined in normal, pathological control, and cystic fibrosis liver homogenates. Cystic fibrosis and pathological livers have about 40% of the average normal specific activity for sialyltransferase.Several properties of ...
J A, Alhadeff, G, Cimino
core +4 more sources
NEW POTENT SIALYLTRANSFERASE INHIBITORS [PDF]
, 2019 The present invention relates to anew class of sialyltransferase inhibitors. The class features a carbamate or similar moiety on the amine of a neuraminic acid derivative. Such inhibitors are suitable for use as a medicament, for example for treating, preventing, or delaying bacterial infection, viral infection, cancer, a disorder of sialic acid ...
Boltje, T.J. +4 more
openaire +3 more sources
Control of sialyltransferase localization and activity.
, 1997 Control of sialyltransferase localization and ...
Jiyan. Ma (7989593)
core +6 more sources
The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach [PDF]
Glycobiology, 2005 The animal sialyltransferases are Golgi type II transmembrane glycosyltransferases. Twenty distinct sialyltransferases have been identified in both human and murine genomes. These enzymes catalyze transfer of sialic acid from CMP-Neu5Ac to the glycan moiety of glycoconjugates. Despite low overall identities, they share four conserved peptide motifs [L (
Harduin-Lepers, Anne +3 more
openaire +3 more sources
Sialyltransferase Activity and Atherosclerosis [PDF]
Circulation Research, 2014 Leukocyte accumulation within the vascular wall is a major feature of atherosclerotic disease and plays crucial roles in the inception, progression, and complications of atherosclerosis. Several coordinated steps converge to promote subendothelial and perivascular accumulation of leukocytes.
Sage, Andrew P, Mallat, Ziad
openaire +3 more sources
Frontiers in Genetics, 2021 Genome wide association meta-analysis identified ST3GAL3, a gene encoding the beta-galactosidase-alpha-2,3-sialyltransferase-III, as a risk gene for attention-deficit/hyperactivity disorder (ADHD).
Olga Rivero +11 more
doaj +1 more source
Journal of Lipid Research, 1993 It has previously been shown that when the molecular species specificity of rat liver Golgi CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase was determined, using as the substrate lactosylceramide (LacCer) incorporated into liposomes ...
H Kadowaki, MA Grant, LA Williams
doaj +1 more source