Results 61 to 70 of about 15,861 (227)

The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease

, 2021
Siglec-1, also known as Sialoadhesin (Sn) and CD169 is highly conserved among vertebrates and with 17 immunoglobulin-like domains is Siglec-1 the largest member of the Siglec family.
Haselhorst, Thomas, Waespy, Mario, Prenzler, Shane, Anoopkumar-Dukie, Shailendra, Rudrawar, Santosh, Kelm, Sorge   +5 more
core   +1 more source

Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells

Frontiers in Immunology, 2023
Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a sialoside-binding receptor expressed by eosinophils and mast cells that exhibits priming status- and cell type-dependent inhibitory activity.
Yun Cao, Clayton H. Rische, Clayton H. Rische, Bruce S. Bochner, Jeremy A. O’Sullivan   +4 more
doaj   +1 more source

Siglec-Fc Binding Assays - Data of Figure 2, 3B, S6B

, 2018
Raw data and statistical analysis of Siglec-Fc binding assays with Neisseria gonorrhoeae ...
Landig, Corinna, Corinna Landig (4614310)   +1 more
core   +1 more source

Comparison of 68Ga-DOTA-Siglec-9 and 18F-Fluorodeoxyribose-Siglec-9 : Inflammation Imaging and Radiation Dosimetry [PDF]

, 2017
Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a ligand of inflammation-inducible vascular adhesion protein-1 (VAP1). We compared Ga-68-DOTA-and F-18-fluorodeoxyribose-(FDR) labeled Siglec-9motif peptides for PET imaging of inflammation ...
Siitonen, Riikka, Helena Virtanen, Liljenback, Heidi, Autio, Anu, Heidi Liljenbäck, Mia Ståhle, Tibor Z. Veres, Knuuti, Juhani, Helariutta, Kerttuli, Xiang-Guo Li, Anu J. Airaksinen, Airaksinen, Anu J., Tolvanen, Tuula, Kerttuli Helariutta, Virtanen, Helena, Antti Saraste, Saraste, Antti, Sirpa Jalkanen, Li, Xiang-Guo, Ståhle, Mia, Roivainen, Anne, Veres, Tibor Z., Jalkanen, Sirpa, Käkelä, Meeri, Anu Autio, Juhani Knuuti, Anne Roivainen, Riikka Siitonen, Tuula Tolvanen, Sanna Hellberg, Johanna M. U. Silvola, Hellberg, Sanna, Meeri Käkelä, Silvola, Johanna M. U.   +33 more
core   +3 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Siglec-1 RNAi interference and competitive inhibition by a GM3 glycan mimetic inhibits HIV-1 VLP internalization by MDMs.

, 2017
(A) MDMs were transfected with 60 nM control or Siglec-1 siRNA on day 8 after plating. Cell lysates were harvested and analyzed by Western blotting for Siglec-1 and actin expression.
Sarah Takushi (3699919), Neal Beeman (3699922), Jason E. Hammonds (3699916), Lingmei Ding (324106), Jaang-Jiun Wang (253626), Gregory B. Melikyan (137795), Paul Spearman (156002), Ashwanth C. Francis (2836463)   +7 more
core   +1 more source

Siglecs at the Host–Pathogen Interface [PDF]

, 2020
Siglecs are sialic acid (Sia) recognizing immunoglobulin-like receptors expressed on the surface of all the major leukocyte lineages in mammals. Siglecs recognize ubiquitous Sia epitopes on various glycoconjugates in the cell glycocalyx and transduce signals to regulate immunological and inflammatory activities of these cells.
Chang, Yung-Chi, Nizet, Victor
openaire   +2 more sources

Comparison of Siglec-1 protein networks and expression patterns in sperm and male reproductive tracts of mice, rats, and humans [PDF]

Veterinary World
Background and Aim: Sialic acid-binding immunoglobulin-like lectin 1 (Siglec-1) is a transmembrane glycoprotein involved in the sialic acid (Sia)-dependent regulation of the immune system.
Hazem Almhanna, Arun HS Kumar, David Kilroy, Gina Duggan, Jane A. Irwin, Bridget Hogg, Colm Reid   +6 more
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Siglec-Fc Binding Assays with gonococcal porins - Fig.4

, 2018
Raw data and statistical analysis of binding assay with Siglec-Fcs and gonococcal ...
Paola Massari (496165), Jerry Fong (6016268), Massari, Paola, Landig, Corinna, Fong, Jerry, Corinna Landig (4614310)   +5 more
core   +1 more source