Results 191 to 200 of about 27,425 (201)

Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation

The Journal of Immunology
Abstract Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell–mediated airway inflammation. Using STAP-1 knockout mice and STAP-1–overexpressing Jurkat cells, we found that STAP-1 enhanced TCR ...
Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, Yuichi Kitai, Ryuta Muromoto, Kenji Oritani, Jun-ichi Kashiwakura, Tadashi Matsuda   +14 more
openaire   +2 more sources

Signal-Transducing Adaptor Protein 1

2020
openaire   +1 more source

STAP-2 Adaptor Protein Regulates Multiple Steps of Immune and Inflammatory Responses

Biological and Pharmaceutical Bulletin, 2021
Tadashi Matsuda, Kenji Oritani
exaly  

Faculty Opinions recommendation of Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2020
openaire   +1 more source

Adaptor Protein STAP-2 Modulates Cellular Signaling in Immune Systems

Biological and Pharmaceutical Bulletin, 2014
Yuichi Sekine
exaly  

Cloning of a Novel Signal-Transducing Adaptor Molecule Containing an SH3 Domain and ITAM

Biochemical and Biophysical Research Communications, 1996
Toshikazu Takeshita, Masaya Higuchi, Kenzo Kaneko   +2 more
exaly  

STAM, Signal Transducing Adaptor Molecule, Is Associated with Janus Kinases and Involved in Signaling for Cell Growth and c-myc Induction

Immunity, 1997
Toshikazu Takeshita, Masaya Higuchi, Hironobu Asao   +2 more
exaly  

Regulation of FcεRI-mediated signaling by an adaptor protein STAP-2/BSK in rat basophilic leukemia RBL-2H3 cells

Biochemical and Biophysical Research Communications, 2003
Yuichi Sekine, Tadashi Matsuda
exaly  

Hrs Is Associated with STAM, a Signal-transducing Adaptor Molecule

Journal of Biological Chemistry, 1997
Hironobu Asao, Nobuyuki Tanaka, Toshikazu Takeshita   +2 more
exaly  

Structural Insight into Modest Binding of a Non-PXXP Ligand to the Signal Transducing Adaptor Molecule-2 Src Homology 3 Domain

Journal of Biological Chemistry, 2003
Tomonori Kaneko, Takashi Kumasaka, Keiji Miyazawa   +2 more
exaly