Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle [PDF]
Proceedings of the National Academy of Sciences, 2007 The signal-recognition particle (SRP) is a ubiquitous protein–RNA complex that targets proteins to cellular membranes for insertion or secretion. A key player in SRP-mediated protein targeting is the evolutionarily conserved core consisting of the SRP RNA and the multidomain protein SRP54.
Tobias, Hainzl +2 more
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Recognition of a signal peptide by the signal recognition particle [PDF]
Nature, 2010 Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome.
Janda, C +5 more
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Concerted Complex Assembly and GTPase Activation in the Chloroplast Signal Recognition Particle [PDF]
, 2011 The universally conserved signal recognition particle (SRP) and SRP receptor (SR) mediate the cotranslational targeting of proteins to cellular membranes.
Chandrasekar, Sowmya +4 more
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Signal recognition particle and SecA cooperate during export of secretory proteins with highly hydrophobic signal sequences. [PDF]
PLoS ONE, 2014 The Sec translocon of bacterial plasma membranes mediates the linear translocation of secretory proteins as well as the lateral integration of membrane proteins.
Yufan Zhou +2 more
doaj +1 more source
Signal Recognition Particle-dependent Membrane Insertion of Mouse Invariant Chain: A Membrane-spanning Protein with a Cytoplasmically Exposed Amino Terminus [PDF]
, 1986 Invariant (Ii) chain is a membrane-spanning protein that is found associated intracellularly with class II histocompatibility antigens. In the endoplasmic reticulum Ii chain spans the membrane and exposes the NH2 terminus on the cytoplasmic and the COOH
Dobberstein, Bernhard, Lipp, Joachim
core +1 more source
Circularization restores signal recognition particle RNA functionality in Thermoproteus
eLife, 2015 Signal recognition particles (SRPs) are universal ribonucleoprotein complexes found in all three domains of life that direct the cellular traffic and secretion of proteins.
André Plagens +3 more
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Support Vector Machines in Analysis of Top Quark Production [PDF]
, 2002 Multivariate data analysis techniques have the potential to improve physics analyses in many ways. The common classification problem of signal/background discrimination is one example. The Support Vector Machine learning algorithm is a relatively new way
A. Vaiciulis, Abachi, Abe, Burges
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Anti-Signal Recognition Particle Myopathy in a Geriatric Patient
European Journal of Case Reports in Internal Medicine, 2015 Anti-signal recognition particle (SRP) myopathy is a rare idiopathic inflammatory myositis that usually affects middle-age women, and is characterized by rapidly progressive proximal and symmetrical muscle weakness, elevated creatine kinase levels ...
Diana Marques Ferreira +4 more
doaj +1 more source
Rolling bearing fault diagnosis based on wavelet packet decomposition and PSO-BPN
Gong-kuang zidonghua, 2020 In view of problems in existing rolling bearing fault diagnosis methods for coal mine rotating machinery, such as incomplete signal feature extraction, low fault diagnosis accuracy and low efficiency, a rolling bearing fault diagnosis method based on ...
JU Chen +5 more
doaj +1 more source
Signal Recognition Particle: An Essential Protein-Targeting Machine [PDF]
, 2013 The signal recognition particle (SRP) and its receptor compose a universally conserved and essential cellular machinery that couples the synthesis of nascent proteins to their proper membrane localization. The past decade has witnessed an explosion in
Akopian, David +3 more
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