Results 11 to 20 of about 8,752,965 (357)
Definitions, 2020 [ Abstract ] Objective : To investigate the effect and mechanism of piceatannol on cerebral ischemia - reperfusion injury. Methods : The oxygen - glucose deprivation reperfu - sion (OGD/R) model was constructed in primary cultured suckling rat cortical ...
Shuyuan Zhang +6 more
semanticscholar +3 more sources
International Journal of Molecular Sciences, 2021 p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
openaire +3 more sources
The role of IL-6/JAK2/STAT3 signaling pathway in cancers
Frontiers in Oncology, 2022 Interleukin-6 (IL-6) is a pleiotropic cytokine involved in immune regulation. It can activate janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) signaling pathway.
Bei Huang, Xiaoling Lang, Xihong Li
semanticscholar +1 more source
Immunity, Inflammation and Disease, 2023 Background Interleukin‐1β (IL‐1β) is a pro‐inflammatory cytokine mainly produced by monocytes and macrophages with a wide range of biological effects.
Peixuan Wang +3 more
doaj +1 more source
Loss of pancreas upon activated Wnt signaling is concomitant with emergence of gastrointestinal identity [PDF]
, 2016 Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays multiple roles during embryonic development including patterning, proliferation and ...
Cano, David A. +7 more
core +8 more sources
Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]
, 2004 Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
core +2 more sources
Jasmonate Signaling Pathway Modulates Plant Defense, Growth, and Their Trade-Offs
International Journal of Molecular Sciences, 2022 Lipid-derived jasmonates (JAs) play a crucial role in a variety of plant development and defense mechanisms. In recent years, significant progress has been made toward understanding the JA signaling pathway. In this review, we discuss JA biosynthesis, as
Cong Li +5 more
semanticscholar +1 more source
Subpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling Pathway. [PDF]
PLoS ONE, 2015 Pathway analysis is a common approach to gain insight from biological experiments. Signaling-pathway impact analysis (SPIA) is one such method and combines both the classical enrichment analysis and the actual perturbation on a given pathway.
Xianbin Li +3 more
doaj +1 more source
Frontiers in Immunology, 2023 Parasitoid wasps control pests via a precise attack leading to the death of the pest. However, parasitoid larvae exhibit self-protection strategies against bracovirus-induced reactive oxygen species impairment.
Xing-Cheng Li +56 more
doaj +1 more source
TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
Frontiers in Pharmacology, 2022 Chronic kidney disease (CKD) was a major public health problem worldwide. Renal fibrosis, especially tubulointerstitial fibrosis, is final manifestation of CKD.
Xiao-yong Yu +4 more
semanticscholar +1 more source