Results 41 to 50 of about 1,569,209 (311)

Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation [PDF]

, 2017
Developing the Wnt pathway inhibitors has been considered as a therapeutic approach for cancers and other Wnt-related diseases. Previously we found that the G-rich sequence of WNT1 promoter is capable of forming G-quadruplex structure and stabilizing ...
Chang, Lien-Cheng;Chen, Tsung-Chih;Chen, Shiag-Jiun;Chen, Chun-Liang;Lee, Chia-Chung;Wu, Shih-Hsiung;Yen, Yun;Huang, Hsu-Shan;Lin, Jing-Jer, 林敬哲   +1 more
core   +1 more source

Genomic alterations of oligodendrogliomas at distant recurrence

Cancer Medicine, 2023
Background Oligodendroglioma is known for its relatively better prognosis and responsiveness to radiotherapy and chemotherapy. However, little is known about the evolution of genetic changes as oligodendroglioma progresses.
Guanzheng Liu, Chaojie Bu, Guangzhong Guo, Zhiyue Zhang, Zhiyuan Sheng, Kaiyuan Deng, Shuang Wu, Sensen Xu, Yage Bu, Yushuai Gao, Meiyun Wang, Gang Liu, Lingfei Kong, Tianxiao Li, Ming Li, Xingyao Bu   +15 more
doaj   +1 more source

The insulin signalling pathway [PDF]

Current Biology, 2002
A key aim for future research is to identify the hydrophobic motif kinase that phosphorylates PKB, S6K, SGK and to establish how this protein kinase(s) is regulated by PtdIns(3,4,5)P3. It is also becoming obvious that the information obtained by the overexpression of constitutively active and dominant negative mutants of protein kinases is not ...
Lizcano, Jose M., Alessi, Dario R.
openaire   +2 more sources

Integrin signaling pathway. [PDF]

, 2013
Integrin signaling pathway.
Josefin Paulsson (436474), Moustapha Hassan (333954), Stefan H. Jacobson (363124), Heevy Abdulkareem Musa Al-Chaqmaqchi (436472), Joachim Lundahl (399256), Ali Moshfegh (399257), Elham Dadfar (436473)   +6 more
core   +1 more source

Signaling Pathways in Gliomas

Genes
Changes in cell signaling pathways, which in normal conditions determine the maintenance of cell homeostasis and the correctness of its basic processes, may cause the transformation of a normal cell into a cancer cell. Alterations in cellular metabolism leading to oncogenesis are considered to be a hallmark of cancer cells.
Stachyra, Paulina, Grzybowska-Szatkowska, Ludmiła   +1 more
openaire   +2 more sources

TGFβ signaling pathway. [PDF]

, 2013
TGFβ signaling pathway.
Josefin Paulsson (436474), Moustapha Hassan (333954), Stefan H. Jacobson (363124), Heevy Abdulkareem Musa Al-Chaqmaqchi (436472), Joachim Lundahl (399256), Ali Moshfegh (399257), Elham Dadfar (436473)   +6 more
core   +1 more source

Research progress on the interaction between ferroptosis and inflammatory signaling pathway

Zhongguo linchuang yanjiu
Ferroptosis is a form of cell death characterized by iron-dependent lipid peroxidation and the accumulation of reactive oxygen species, distinct from apoptosis and other forms of cell death.
LI Yaling, BAI Yihua, FAN Yang, HUANG Lilan
doaj   +1 more source

Proposed signaling pathway. [PDF]

, 2019
Proposed signaling pathway.
Mohamed Chakkour (4872478), Sawsan Kreydiyyeh (7164767), Layla El Moussawi (4872475)   +2 more
core   +1 more source

Interleukin signaling pathway. [PDF]

, 2013
Interleukin signaling pathway.
Josefin Paulsson (436474), Moustapha Hassan (333954), Stefan H. Jacobson (363124), Heevy Abdulkareem Musa Al-Chaqmaqchi (436472), Joachim Lundahl (399256), Ali Moshfegh (399257), Elham Dadfar (436473)   +6 more
core   +1 more source

HOXA10 enhances cell proliferation and suppresses apoptosis in esophageal cancer via activating p38/ERK signaling pathway

Open Medicine, 2022
Esophageal cancer (EC) is an extremely aggressive malignant tumor. Homeobox A10 (HOXA10) is highly expressed and plays an important role in a variety of tumors. However, the function of HOXA10 in EC remains unclear.
Jiang Lifeng, Yang Qixian
doaj   +1 more source