Results 51 to 60 of about 1,526,064 (264)
Signaling the Pathway to Regeneration [PDF]
Neuron, 2002 Robust axon regeneration occurs after peripheral nerve injury through coordinated activation of a genetic program and local intracellular signaling cascades. Although regeneration-associated genes are being identified with increasing frequency, most aspects of regeneration-associated intracellular signaling remain poorly understood.
Snider, William D. +3 more
openaire +2 more sources
The sensory system acts with a neuromedin U signaling pathway to mediate food type-dependent effects on lifespan [PDF]
, 2010 In order to survive, the animal uses its sensory system to interpret the complexity of its environment. Interestingly, a subset of sensory neurons, which function in taste or olfaction, has been found to influence the lifespan of C.
Adilov, Bakhtiyor
core +1 more source
Research progress on the interaction between ferroptosis and inflammatory signaling pathway
Zhongguo linchuang yanjiuFerroptosis is a form of cell death characterized by iron-dependent lipid peroxidation and the accumulation of reactive oxygen species, distinct from apoptosis and other forms of cell death.
LI Yaling, BAI Yihua, FAN Yang, HUANG Lilan
doaj +1 more source
Animals, 2021 Chicken is important livestock that serves as a vital food source which remain largely affected by heat stress. Therefore, we performed the transcriptome analysis to help understand the mechanisms of heat stress response in chickens.
Hana Kim +6 more
doaj +1 more source
Molecular networks in FGF signaling: Flotillin-1 and Cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2 [PDF]
, 2012 Fibroblast growth factor receptor substrate 2 (FRS2α) is a signaling adaptor protein that regulates downstream signaling of many receptor tyrosine kinases.
Traub Stephanie +11 more
core +2 more sources
Exploring the mechanisms of lithium neurotoxicity based on network toxicology and molecular docking
Ecotoxicology and Environmental SafetyThe rapid growth of lithium (Li)-related industrial activities and the application of Li-containing products have become an emerging human health concern.
Wei Wei +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Signal transduction pathways to apoptosis [PDF]
Trends in Cell Biology, 1994 Recent work has demonstrated that a number of signalling events, including cytosolic Ca(2+) rises, cAMP accumulation, activation of protein kinase C, activation of protein tyrosine kinases, and production of ceramide, regulate apoptosis in diverse model systems.
D J, McConkey, S, Orrenius
openaire +3 more sources
Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]
, 2014 This work was supported by grants from Breakthrough Breast Cancer and Scottish Funding Council (SRDG), and personal support to Alexey Goltsov from Scottish Informatics and Computer Science Alliance (SICSA) and to James Bown from The Northwood Trust.Drug ...
Bown, James +22 more
core +1 more source
“Biomechanical Signaling in Oocytes and Parthenogenetic Cells”
Frontiers in Cell and Developmental Biology, 2021 Oocyte-specific competence remains one of the major targets of current research in the field of reproduction. Several mechanisms are involved in meiotic maturation and the molecular signature of an oocyte is considered to reflect its quality and to ...
Georgia Pennarossa +2 more
doaj +1 more source