Results 21 to 30 of about 1,569,209 (311)

Signaling the Pathway to Regeneration [PDF]

open access: yesNeuron, 2002
Robust axon regeneration occurs after peripheral nerve injury through coordinated activation of a genetic program and local intracellular signaling cascades. Although regeneration-associated genes are being identified with increasing frequency, most aspects of regeneration-associated intracellular signaling remain poorly understood.
Snider, William D.   +3 more
openaire   +2 more sources

The Jasmonate Signal Pathway [PDF]

open access: yesThe Plant Cell, 2002
Plant responses to many biotic and abiotic stresses are orchestrated locally and systemically by signaling molecules known as the jasmonates (JAs). JAs also regulate such diverse processes as pollen maturation and wound responses in Arabidopsis.
Turner, J.G.   +2 more
openaire   +10 more sources

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

open access: yes, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M.   +45 more
core   +1 more source

Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction

open access: yesRedox Biology, 2022
Notoginsenoside R1 (NGR1) is the main monomeric component extracted from the dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against myocardial infarction (MI).
Han Li   +15 more
doaj   +1 more source

Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice

open access: yesFrontiers in Plant Science, 2017
High-salinity stress considerably affects plant growth and crop yield. Thus, developing techniques to enhance high-salinity stress tolerance in plants is important.
Huong Mai Nguyen   +15 more
doaj   +1 more source

Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling [PDF]

open access: yes, 2011
Genome-wide association studies (GWAS) have identified SNPs associated with breast cancer. However, they offer limited insights about the biological mechanisms by which SNPs confer risk.
Chindo Hicks   +2 more
core   +1 more source

The Signaling Pathway of Rhodopsin [PDF]

open access: yesStructure, 2007
The signal-transduction mechanism of rhodopsin was studied by molecular dynamics (MD) simulations of the high-resolution, inactive structure in an explicit membrane environment. The simulations were employed to calculate equal-time correlations of the fluctuating interaction energy of residue pairs. The resulting interaction-correlation matrix was used
Kong, Yifei, Karplus, Martin
openaire   +2 more sources

Endothelial-derived APT1-mediated macrophage-endothelial cell interactions participate in the development of atherosclerosis by regulating the Ras/MAPK signaling pathway [PDF]

open access: yes, 2022
Acyl-protein thioesterase 1 (APT1) can affect H-Ras localization and function by promoting its depalmitoylation. However, relatively little attention has been paid to the effects of APT1 on H-Ras in the cardiovascular system.
Tse, Gary   +6 more
core   +1 more source

Fungal Elicitation of Signal Transduction-Related Plant Genes Precedes Mycorrhiza Establishment and Requires the dmi3 Gene in Medicago truncatula

open access: yesMolecular Plant-Microbe Interactions, 2004
Suppressive subtractive hybridization and expressed sequence tag sequencing identified 29 plant genes which are upregulated during the appressorium stage of mycorrhiza establishment between Medicago truncatula J5 (Myc+) and Glomus mosseae.
Stéphanie Weidmann   +5 more
doaj   +1 more source

A Single-Cell Atlas of an Early Mongolian Sheep Embryo

open access: yesVeterinary Sciences, 2023
Cell types have been established during organogenesis based on early mouse embryos. However, our understanding of cell types and molecular mechanisms in the early embryo development of Mongolian sheep has been hampered.
Tingyi He   +17 more
doaj   +1 more source

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