Results 11 to 20 of about 1,526,064 (264)

Wnt signaling pathway in retinal vascularization

open access: yesEye and Brain, 2016
Kimberly A Drenser Associated Retinal Consultants, Royal Oak, MI, USA Abstract: Wnt-signaling, a ubiquitous pathway that directs differentiation, cell polarity, and tissue specificity, has been implicated as an important gene-expression pathway in ...
Drenser KA
doaj   +1 more source

p38 Signalling Pathway [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
openaire   +3 more sources

A review of signal pathway induced by virulent protein CagA of Helicobacter pylori

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Gastric cancer (GC), a common and high-mortality disease, still occupies an important position in current cancer research, and Helicobacter pylori (H. pylori) infection as its important risk factor has been a hot and challenging research area.
Haiqiang Wang   +5 more
doaj   +1 more source

Signaling Pathways in Pregnancy

open access: yesCells, 2022
We are pleased to present this Special Issue of Cells, entitled ‘Signaling Pathways in Pregnancy’ [...]
Giovanni Tossetta, Daniela Marzioni
openaire   +3 more sources

Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish

open access: yesBiology, 2021
Long-term imbalance between fatigue and recovery may eventually lead to muscle weakness or even atrophy. We previously reported that excessive exercise induces pathological cardiac hypertrophy.
Chen-Chen Sun   +7 more
doaj   +1 more source

Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing data

open access: yesFrontiers in Genetics, 2022
Osteosarcoma (OS) is a common bone cancer in children and adolescents, and metastasis and recurrence are the major causes of poor treatment outcomes. A better understanding of the tumor microenvironment is required to develop an effective treatment for ...
Ning Xu   +6 more
doaj   +1 more source

Signaling Pathways in Melanogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Melanocytes are melanin-producing cells found in skin, hair follicles, eyes, inner ear, bones, heart and brain of humans. They arise from pluripotent neural crest cells and differentiate in response to a complex network of interacting regulatory pathways. Melanins are pigment molecules that are endogenously synthesized by melanocytes.
Stacey D’Mello   +3 more
openaire   +3 more sources

Role of signal transduction pathways in IL‐1β‐induced apoptosis: Pathological and therapeutic aspects

open access: yesImmunity, Inflammation and Disease, 2023
Background Interleukin‐1β (IL‐1β) is a pro‐inflammatory cytokine mainly produced by monocytes and macrophages with a wide range of biological effects.
Peixuan Wang   +3 more
doaj   +1 more source

Keap1/Nrf2 Signaling Pathway

open access: yesAntioxidants, 2021
Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of ...
Gerasimos P. Sykiotis
doaj   +1 more source

Signaling on the endocytic pathway [PDF]

open access: yesCurrent Opinion in Cell Biology, 2007
Endocytosis regulates many cellular signaling processes by controlling the number of functional receptors available at the cell surface. Conversely, some signaling processes regulate the endocytic pathway. Furthermore, various cellular signaling events appear to occur on endosome membranes.
Mark, von Zastrow, Alexander, Sorkin
openaire   +2 more sources

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