Results 11 to 20 of about 1,424,654 (267)
Keap1/Nrf2 Signaling Pathway [PDF]
Antioxidants, 2021 Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of ...
Gerasimos P. Sykiotis
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International Journal of Molecular Sciences, 2021 p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
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A review of signal pathway induced by virulent protein CagA of Helicobacter pylori
Frontiers in Cellular and Infection Microbiology, 2023 Gastric cancer (GC), a common and high-mortality disease, still occupies an important position in current cancer research, and Helicobacter pylori (H. pylori) infection as its important risk factor has been a hot and challenging research area.
Haiqiang Wang +5 more
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Biology, 2021 Long-term imbalance between fatigue and recovery may eventually lead to muscle weakness or even atrophy. We previously reported that excessive exercise induces pathological cardiac hypertrophy.
Chen-Chen Sun +7 more
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Frontiers in Genetics, 2022 Osteosarcoma (OS) is a common bone cancer in children and adolescents, and metastasis and recurrence are the major causes of poor treatment outcomes. A better understanding of the tumor microenvironment is required to develop an effective treatment for ...
Ning Xu +6 more
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Immunity, Inflammation and Disease, 2023 Background Interleukin‐1β (IL‐1β) is a pro‐inflammatory cytokine mainly produced by monocytes and macrophages with a wide range of biological effects.
Peixuan Wang +3 more
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Subpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling Pathway. [PDF]
PLoS ONE, 2015 Pathway analysis is a common approach to gain insight from biological experiments. Signaling-pathway impact analysis (SPIA) is one such method and combines both the classical enrichment analysis and the actual perturbation on a given pathway.
Xianbin Li +3 more
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SnapShot: PTEN Signaling Pathways [PDF]
Cell, 2008 is causative for familial diseases including Cowden syndrome, which is characterized by multiple hamartomas, developmental defects, and increased cancer susceptibility.The major tumor-suppressive activity of PTEN is attributed to its ability to hydrolyze the 3′ phosphate of phosphoinositides at the plasma membrane and thereby negatively regulate ...
Carracedo A +2 more
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Frontiers in Immunology, 2023 Parasitoid wasps control pests via a precise attack leading to the death of the pest. However, parasitoid larvae exhibit self-protection strategies against bracovirus-induced reactive oxygen species impairment.
Xing-Cheng Li +56 more
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Rice, 2018 Background Magnaporthe oryzae, the causal fungus of rice blast disease, negatively impacts global rice production. Wild rice (Oryza rufipogon), a relative of cultivated rice (O.
Lei Tian +6 more
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