Results 11 to 20 of about 1,526,064 (264)
Wnt signaling pathway in retinal vascularization
Kimberly A Drenser Associated Retinal Consultants, Royal Oak, MI, USA Abstract: Wnt-signaling, a ubiquitous pathway that directs differentiation, cell polarity, and tissue specificity, has been implicated as an important gene-expression pathway in ...
Drenser KA
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p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
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A review of signal pathway induced by virulent protein CagA of Helicobacter pylori
Gastric cancer (GC), a common and high-mortality disease, still occupies an important position in current cancer research, and Helicobacter pylori (H. pylori) infection as its important risk factor has been a hot and challenging research area.
Haiqiang Wang +5 more
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Signaling Pathways in Pregnancy
We are pleased to present this Special Issue of Cells, entitled ‘Signaling Pathways in Pregnancy’ [...]
Giovanni Tossetta, Daniela Marzioni
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Long-term imbalance between fatigue and recovery may eventually lead to muscle weakness or even atrophy. We previously reported that excessive exercise induces pathological cardiac hypertrophy.
Chen-Chen Sun +7 more
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Osteosarcoma (OS) is a common bone cancer in children and adolescents, and metastasis and recurrence are the major causes of poor treatment outcomes. A better understanding of the tumor microenvironment is required to develop an effective treatment for ...
Ning Xu +6 more
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Signaling Pathways in Melanogenesis [PDF]
Melanocytes are melanin-producing cells found in skin, hair follicles, eyes, inner ear, bones, heart and brain of humans. They arise from pluripotent neural crest cells and differentiate in response to a complex network of interacting regulatory pathways. Melanins are pigment molecules that are endogenously synthesized by melanocytes.
Stacey D’Mello +3 more
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Background Interleukin‐1β (IL‐1β) is a pro‐inflammatory cytokine mainly produced by monocytes and macrophages with a wide range of biological effects.
Peixuan Wang +3 more
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Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of ...
Gerasimos P. Sykiotis
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Signaling on the endocytic pathway [PDF]
Endocytosis regulates many cellular signaling processes by controlling the number of functional receptors available at the cell surface. Conversely, some signaling processes regulate the endocytic pathway. Furthermore, various cellular signaling events appear to occur on endosome membranes.
Mark, von Zastrow, Alexander, Sorkin
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