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Signaling pathways in context

Current Opinion in Biotechnology, 2019
The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system.
Friedemann, Uschner, Edda, Klipp
openaire   +2 more sources

Signaling pathways in glioblastoma

Critical Reviews in Oncology/Hematology
Cancer is one of the main public health problems worldwide. Among tumors of the Central Nervous System (CNS), glioblastoma (GBM) affects 49.1 % of malignant brain tumors, and despite standard treatment, patients diagnosed with GBM have a dismal prognosis, a high rate of recurrence after tumor resection and poor survival.
Isabella Gomes   +2 more
openaire   +2 more sources

Basophil Stimulation and Signaling Pathways

2014
Despite the growing use of flow cytometry to analyze the functional characteristics of basophils, the intracellular signaling cascades that control their ability to elaborate various pro-allergic and inflammatory mediators and cytokines remain comparatively obscure.
Edward F, Knol, Bernhard F, Gibbs
openaire   +3 more sources

Crossroads of Signaling Pathways

2013
As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences of mutations and epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm of these tumors.
openaire   +2 more sources

The Insulin Signaling Pathway

The Journal of Membrane Biology, 1999
C, Taha, A, Klip
openaire   +2 more sources

The Wnt signalling pathway

Journal of Cell Science, 2000
J, Hlsken, J, Behrens
openaire   +2 more sources

Calcium-calcineurin signaling pathway in Candida albicans: A potential drug target

Microbiological Research, 2021
Hui Lu   +2 more
exaly  

Progress of Wnt Signaling Pathway in Osteoporosis

Biomolecules, 2023
Yongguang Gao, , Gao Yongguang
exaly  

Hippo Signaling Pathway in Gliomas

Cells, 2021
Lucie Karayan Tapon   +2 more
exaly  

The role of JAK/STAT signaling pathway and its inhibitors in diseases

International Immunopharmacology, 2020
Shuang Liu, Youzhi Wang
exaly  

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