Results 31 to 40 of about 2,211,530 (330)
Signaling on the Endocytic Pathway [PDF]
Traffic, 2001 Ligand binding to receptor tyrosine kinases and G‐protein‐coupled receptors initiates signal transduction events and induces receptor endocytosis via clathrin‐coated pits and vesicles. While receptor‐mediated endocytosis has been traditionally considered an effective mechanism to attenuate ligand‐activated responses, more recent studies demonstrate ...
Natasha K. Hussain +2 more
openaire +3 more sources
Integrated analysis of microRNA and mRNA expression profiles in Preeclampsia
BMC Medical Genomics, 2023 Background Preeclampsia (PE), a pregnancy specific syndrome, is one kind of common gestational hypertension disease, which can cause maternal and perinatal mortality and morbidity.
Zepeng Ping +4 more
doaj +1 more source
The Role of Curcumin in Cancer Treatment
Biomedicines, 2021 Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated with the development of cancer.
Vasiliki Zoi +5 more
doaj +1 more source
Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
core +2 more sources
Exercise-induced signaling pathways to counteracting cardiac apoptotic processes
Frontiers in Cell and Developmental Biology, 2022 Cardiovascular diseases are the most common cause of death in the world. One of the major causes of cardiac death is excessive apoptosis. However, multiple pathways through moderate exercise can reduce myocardial apoptosis.
Hamed Alizadeh Pahlavani
doaj +1 more source
Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]
, 2013 Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core +1 more source
The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis [PDF]
, 2020 Purpose: Aberrant expression of microRNAs (miRNAs) has been discovered in prostate cancer progression however their function is not well understood, thereby further investigation is required to understand the importance of underlying mechanisms and their
Arisan, E.D. +9 more
core +1 more source
Frontiers in Physiology, 2021 Aim: Chitinase 3-like 1 (CHI3L1) has the potential to prompt proliferation and angiogenic formation. Interleukin-13 receptor α2 (IL-13Rα2) was regarded as a receptor of CHI3L1; however, it is unknown whether CHI3L1 adjusts the neovascularization in late ...
Qi Xue +6 more
doaj +1 more source
Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. [PDF]
, 2017 Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways.
Murley, Andrew +6 more
core +1 more source
International Journal of Molecular Sciences, 2023 Cancer is a major health-threatening disease and is the second leading cause of death worldwide; the prevention and treatment of cancer remains one of the most challenging problems clinically [...]
openaire +2 more sources