Diversity in viral anti-PKR mechanisms: A remarkable case of evolutionary convergence [PDF]
, 2015 Most viruses express during infection products that prevent or neutralize the effect of the host dsRNA activated protein kinase (PKR). Translation of Sindbis virus (SINV) mRNA escapes to PKR activation and eIF2 phosphorylation in infected cells by a ...
Domingo-Gil, Elena +4 more
core +1 more source
Voprosy virusologiiHerpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family. Smoking is one of the leading causes of disease and premature death worldwide, responsible for the death of up to six million people annually.
Jalil B. Mays +2 more
openaire +2 more sources
A full UL13 open reading frame in Marek’s disease virus (MDV) is dispensable for tumor formation and feather follicle tropism and cannot restore horizontal virus transmission of rRB-1B in vivo [PDF]
, 2007 peer reviewedMarek’s disease virus (MDV) is an oncogenic alphaherpesvirus that is highly contagious in poultry. Recombinant RB-1B (rRB-1B) reconstituted from an infectious genome cloned as a bacterial artificial chromosome (BAC) is unable to spread ...
Beaumont, Catherine +6 more
core +3 more sources
Evidence and knowledge gaps on the disease burden in sexual and gender minorities : a review of systematic reviews [PDF]
, 2016 Sexual and gender minorities (SGM) include individuals with a wide range of sexual orientations, physical characteristics, and gender identities and expressions.
Blondeel, Karel +6 more
core +1 more source
Measurement and predictors of adherence in a trial of HSV suppressive therapy in Tanzania.
, 2009 This study estimates adherence and identifies predictors of good adherence among 1305 Tanzanian women participating in a randomised, double-blind, placebo-controlled trial of HSV suppressive therapy to reduce HIV incidence or genital HIV shedding.
Baisley, Kathy +10 more
core +1 more source
Antiviral activity of Holothuria sp. a sea cucumber against herpes simplex virus type 1 (HSV-1) [PDF]
, 2014 BACKGROUND: Finding the new bioactive compounds with antiviral activity from the natural resources are in interest of many drug discovery scientists.
AMIRINEJAD, R. +6 more
core +1 more source
, 2018 Herpes simplexvirus 1 och 2 orsakar godartade sjukdomar, men kan även orsaka mortalitet. Diagnostik av herpes simplexvirus 1 och 2 utförs numera framför allt med realtids- Polymerase chain reaction (PCR). I metoden amplifieras specifika deoxiribonukleinsyra(DNA)-sekvenser till miljontals kopior vilka sedan detekteras med fluorescein.
Karlsson, Samuel, Palma Jansson, Nelly
openaire +1 more source
Characteristics of the pulmonary microbiota in patients with mild and severe pulmonary infection. [PDF]
Front Cell Infect Microbiol, 2023 Zhan D +6 more
europepmc +1 more source
Expression of ICP0 from the simian simplexvirus SA8 and a study of its transactivation activity
, 2011 Human Herpes Simplex viruses and Simian Herpes Simplex viruses share a high degree of genome homology, but despite this, important differences arise when the viruses are compared at the level of gene expression and virulence in non-host primates. In Human Herpes viruses (HSV-1 and HSV-2); 5 genes (RL02, US01, RS01, UL54 and US12) are expressed with an ...
openaire +1 more source