Results 181 to 190 of about 1,893 (191)

Nobiletin, sinensetin, and tangeretin are the main perpetrators in clementines provoking food-drug interactions in vitro

Food Chemistry, 2020
For clementine juice, previous data indicate a possible food-drug interaction with substrates of key enzymes responsible for drug metabolism (i.e. cytochrome P450 [CYP] 3A4, CYP1A2). However, which compounds in clementine juice are responsible for these effects are unknown.
Johanna Weiss, Giuseppe Gattuso, Davide Barreca, Walter Emil Haefeli   +3 more
openaire   +3 more sources

Investigation of synergistic interaction of sinensetin, eupatorin, and 3′-hydroxy-5,6,7,4′-tetramethoxyflavone in vasodilation efficacy

Hypertension Research
Modern medicines often follow a "single-compound, single-target" paradigm, which may not be effective against complex diseases with multifactorial causes. Medicinal plants, such as Orthosiphon stamineus-widely used in Southeast Asia for its significant vasodilatory and antihypertensive properties-offer an alternative.
Mun Fei, Yam, Wan Yin, Tew, Chu Shan, Tan, Qiyue, Qiu, Ruixian, Zhou, Xuye, Wang, Yau Pin, Yap, Wei, Xu, Wen, Xu, Lai Kuan, Teh   +9 more
openaire   +2 more sources

In vivo metabolic fates of sinensetin, 5-demethylsinensetin and their metabolites under diverse conditions

2022
Citrus polymethoxyflavones (PMFs) have attracted great research interest since the recent decade. However, the existed investigations mainly focused on the potential bioactivities of those PMFs, and paid little attention to the in vivo metabolic fates of them.
openaire   +1 more source

Sinensetin Inhibits Angiogenesis in Lung Adenocarcinoma via the miR-374c-5p/VEGF-A/VEGFR-2/AKT Axis

Cell Biochemistry and Biophysics
Sinensetin is a product isolated from Orthosiphon aristatus, and its antitumor activities have been well established. This study focused on the role and mechanism of sinensetin in lung adenocarcinoma (LUAD). LUAD cells were treated with various concentrations of sinensetin.
Tao, Ji, Lin, Ye, Erping, Xi, Ying, Liu, Xiumei, Wang, Sha, Wang   +5 more
exaly   +3 more sources

Inhibitory mechanism of sinensetin on α-glucosidase and non-enzymatic glycation: Insights from spectroscopy and molecular docking analyses

International Journal of Biological Macromolecules, 2021
Xiang-Yu Cao, Yu-Chi Kong, Jian-Li Liu
exaly  

Sinensetin attenuates oxygen–glucose deprivation/reperfusion‐induced neurotoxicity by MAPK pathway in human cerebral microvascular endothelial cells

Journal of Applied Toxicology, 2022
Tiancai Wang
exaly  

Parametric and kinetic study of supercritical carbon dioxide extraction on sinensetin from Orthosiphon stamineus Benth. leaves

Separation Science and Technology, 2022
Ahmad Hazim Abdul Aziz, Nicky Rahmana Putra, Mohd Azizi Che Yunus   +2 more
exaly  

Effects of Sinensetin on Lipid Metabolism in Mature 3T3‐L1 Adipocytes

Phytotherapy Research, 2013
Se-Jae Kim
exaly  

Dietary sinensetin and polymethoxyflavonoids: Bioavailability and potential metabolic syndrome-related bioactivity

Critical Reviews in Food Science and Nutrition
Mutang Zhang
exaly  

A Simple Isocratic HPLC Method for the Simultaneous Determination of Sinensetin, Eupatorin, and 3′-hydroxy-5,6,7,4′-tetramethoxyflavone in Orthosiphon stamineus Extracts

JAMS Journal of Acupuncture and Meridian Studies, 2012
Mun Fei Yam, Roziahanim B Mahmud, Mohd Zaini Asmawi   +2 more
exaly