Results 161 to 170 of about 1,893 (191)
Some of the next articles are maybe not open access.
Critical Reviews in Food Science and Nutrition, 2023
Sinensetin is among the most ubiquitous polyphenols in citrus fruit and recently has been extensively studied for its ability to prevent or treat diseases. The current literature on the bioavailability of sinensetin and its derivatives was reviewed and the potential ameliorative effects of metabolic syndrome in humans were evaluated. Sinensetin and its
Mutang Zhang +8 more
openaire +2 more sources
Sinensetin is among the most ubiquitous polyphenols in citrus fruit and recently has been extensively studied for its ability to prevent or treat diseases. The current literature on the bioavailability of sinensetin and its derivatives was reviewed and the potential ameliorative effects of metabolic syndrome in humans were evaluated. Sinensetin and its
Mutang Zhang +8 more
openaire +2 more sources
Quantification and enrichment of sinensetin in the leaves of Orthosiphon stamineus
Arabian Journal of Chemistry, 2016 AbstractSinensetin was identified in the leaves of Orthosiphon stamineus by thin-layer chromatography, GC coupled with mass spectrometry (MS), UV, IR and 1H-NMR spectroscopy. Enrichment of sinensetin by using different mixture solvent system and the quantification analysis by thin-layer chromatography-imaging densitometric method using as external ...
Mohammad Amzad Hossain
exaly +2 more sources
Chemie in Unserer Zeit, 2013
AbstractSinensetin wurde aus kaltgepresstem Orangenschalenöl isoliert und aus Ethanol umkristallisiert. Alle analytischen Spektren sind vollständig entweder im Hauptteil oder im online unter www.chiuz.de zusätzlichen Material zu diesem Artikel wiedergegeben.
Dieter Sicker, Stefan Berger
exaly +3 more sources
AbstractSinensetin wurde aus kaltgepresstem Orangenschalenöl isoliert und aus Ethanol umkristallisiert. Alle analytischen Spektren sind vollständig entweder im Hauptteil oder im online unter www.chiuz.de zusätzlichen Material zu diesem Artikel wiedergegeben.
Dieter Sicker, Stefan Berger
exaly +3 more sources
Die Pharmazie, 2022
In this study, we investigated the immunomodulatory effects of sinensetin (SI) on RAW 264.7 macrophages and cyclophosphamide (CY)-induced immunosuppressed mice. The results showed that SI enhanced macrophage activity and promoted the secretion of NO, IL-1β, and TNF-α in vitro. Compared with the CY-induced immunosuppressed mice, in mice treated with SI,
Yi-Lun Wang, Yi-Lun Wang +2 more
openaire +2 more sources
In this study, we investigated the immunomodulatory effects of sinensetin (SI) on RAW 264.7 macrophages and cyclophosphamide (CY)-induced immunosuppressed mice. The results showed that SI enhanced macrophage activity and promoted the secretion of NO, IL-1β, and TNF-α in vitro. Compared with the CY-induced immunosuppressed mice, in mice treated with SI,
Yi-Lun Wang, Yi-Lun Wang +2 more
openaire +2 more sources
Biochemical and Biophysical Research Communications, 2002
Multidrug resistance (MDR) cells can be sensitized to anticancer drugs when treated concomitantly with chemosensitizers. In this study, chemosensitizing effects of 5,6,7,3',4'-pentamethoxyflavone (sinensetin) and its analogs were investigated with respect to in vitro efficacy and structure-activity relationship.
Jin Cheol Yoo, Jae-Kyung Sohng
exaly +3 more sources
Multidrug resistance (MDR) cells can be sensitized to anticancer drugs when treated concomitantly with chemosensitizers. In this study, chemosensitizing effects of 5,6,7,3',4'-pentamethoxyflavone (sinensetin) and its analogs were investigated with respect to in vitro efficacy and structure-activity relationship.
Jin Cheol Yoo, Jae-Kyung Sohng
exaly +3 more sources
Sinensetin Attenuates LPS-Induced Inflammation by Regulating the Protein Level of IκB-α
Bioscience, Biotechnology and Biochemistry, 2012Sinensetin is one of the polymethoxyflavones (PMFs) having five methoxy groups on the basic benzo-γ-pyrone skeleton with a carbonyl group at the C(4) position. We investigated in this study the anti-inflammatory activity of sinensetin in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
Se-Jae Kim
exaly +3 more sources
Journal of Agricultural and Food Chemistry, 2021
As one of the major polymethoxyflavones in citrus peels, sinensetin (Sin) has been reported to possess numerous bioactivities. However, its detailed in vivo metabolic fate has not been uncovered yet. In the present study, the possible metabolites of Sin were synthesized, and all five mono-demethylated metabolites were successfully identified via ...
Xiaoqi Wang, Dong-Li Li, Yong Cao
exaly +3 more sources
As one of the major polymethoxyflavones in citrus peels, sinensetin (Sin) has been reported to possess numerous bioactivities. However, its detailed in vivo metabolic fate has not been uncovered yet. In the present study, the possible metabolites of Sin were synthesized, and all five mono-demethylated metabolites were successfully identified via ...
Xiaoqi Wang, Dong-Li Li, Yong Cao
exaly +3 more sources
Food & Function, 2022
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degeneration, subchondral bone sclerosis, synovial hyperplasia and osteophyte formation as the main pathological manifestations.
Zhendong Liu +6 more
openaire +2 more sources
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degeneration, subchondral bone sclerosis, synovial hyperplasia and osteophyte formation as the main pathological manifestations.
Zhendong Liu +6 more
openaire +2 more sources
Sinensetin protects against pulmonary fibrosis via inhibiting Wnt/β-Catenin signaling pathway
Tissue and Cell, 2022Pulmonary fibrosis is a fatal lung disease characterized by progressive fibroblast proliferation and extensive extracellular matrix (ECM) deposition. Although great efforts have been placed to understand the pathogenesis and explore therapeutic strategies, the treatment options for pulmonary fibrosis are very limited and the prognosis of pulmonary ...
Xuan, Wan +5 more
exaly +3 more sources
Pharmacological Research, 2019 Intestinal epithelial barrier dysfunction is a key pathology of colitis. Autophagy of epithelial cells maintains homeostasis of the intestinal barrier by inhibiting apoptosis and stimulating degradation of the tight junction protein claudin-2. This study investigated the effects and mechanism of activity of sinensetin, a polymethylated flavonoid ...
Dapeng Chen
exaly +3 more sources