Results 31 to 40 of about 1,166,241 (315)

A Single-Cell Sequencing Guide for Immunologists [PDF]

Frontiers in Immunology, 2018
In recent years there has been a rapid increase in the use of single-cell sequencing (scRNA-seq) approaches in the field of immunology. With the wide range of technologies available, it is becoming harder for users to select the best scRNA-seq protocol/platform to address their biological questions of interest.
Peter See, Josephine Lum, Jinmiao Chen, Florent Ginhoux, Florent Ginhoux   +4 more
openaire   +3 more sources

Advances in application of single-cell RNA sequencing in cardiovascular research

Frontiers in Cardiovascular Medicine, 2022
Single-cell RNA sequencing (scRNA-seq) provides high-resolution information on transcriptomic changes at the single-cell level, which is of great significance for distinguishing cell subtypes, identifying stem cell differentiation processes, and ...
Yue Hu, Ying Zhang, Yutong Liu, Yan Gao, Tiantian San, Xiaoying Li, Xiaoying Li, Sensen Song, Binglong Yan, Zhuo Zhao, Zhuo Zhao   +10 more
doaj   +1 more source

Challenges and opportunities to computationally deconvolve heterogeneous tissue with varying cell sizes using single-cell RNA-sequencing datasets

Genome Biology, 2023
Deconvolution of cell mixtures in “bulk” transcriptomic samples from homogenate human tissue is important for understanding disease pathologies. However, several experimental and computational challenges impede transcriptomics-based deconvolution ...
Sean K. Maden, Sang Ho Kwon, Louise A. Huuki-Myers, Leonardo Collado-Torres, Stephanie C. Hicks, Kristen R. Maynard   +5 more
doaj   +1 more source

Single-cell RNA sequencing of human kidney

, 2023
A comprehensive cellular anatomy of normal human kidney is crucial to address the cellular origins of renal disease and renal cancer. Some kidney diseases may be cell type-specific, especially renal tubular cells.
huan yang (17600760)
core   +1 more source

Single-Cell Sequencing of Hepatocellular Carcinoma Reveals Cell Interactions and Cell Heterogeneity in the Microenvironment

International Journal of General Medicine, 2021
Xinyao Li,1 Lei Wang,1 Liusong Wang,1 Zanjie Feng,2 Cijun Peng1 1Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, People’s Republic of China; 2Department of Biochemistry and Molecular Biology ...
Li X, Wang L, Wang L, Feng Z, Peng C
doaj  

Single-cell RNA Sequencing in Immunology

Current Genomics, 2020
The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases.
Yirui Cao, Yue Qiu, Guowei Tu, Cheng Yang   +3 more
openaire   +3 more sources

Applications of Single-Cell Sequencing in Dermatology

Medical Science Monitor, 2021
Single-cell sequencing (SCS) is a promising new technique used to assess the genomics, transcriptomics, epigenetics, and other multi-omics at the single-cell level. In addition to elucidating the immune microenvironment and revealing the pathomechanisms of disease and drug resistance, SCS can profile the actual state of an individual cell and identify ...
Zou, Dandan, Qi, Jue, Wu, Wenjuan, Xu, Dan, Tu, Ying, Liu, Tongyun, Zhang, Juan, Li, Xing, Lu, Fengyan, He, Li   +9 more
openaire   +3 more sources

Single Cell RNA Sequencing of Rare Immune Cell Populations

Frontiers in Immunology, 2018
Single-cell RNA sequencing (scRNA-Seq) is transforming our ability to characterize cells, particularly rare cells that are often overlooked in bulk population analytical approaches.
Akira Nguyen, Akira Nguyen, Weng Hua Khoo, Weng Hua Khoo, Imogen Moran, Imogen Moran, Peter I. Croucher, Peter I. Croucher, Tri Giang Phan, Tri Giang Phan   +9 more
doaj   +1 more source

Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease

, 2023
In this thesis, the main scientific pursuit is that of leveraging information from genome-wide association studies (GWAS) in combination with gene expression datasets such as to narrow down the list of genes and cell-types that may be important for ...
Voda, Alexandru
core   +1 more source

Screening of cell‐virus, cell‐cell, gene‐gene crosstalk among animal kingdom at single cell resolution

Clinical and Translational Medicine, 2022
Background The exact animal origin of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) remains obscure and understanding its host range is vital for preventing interspecies transmission.
Dongsheng Chen, Zhihua Ou, Jiacheng Zhu, Haoyu Wang, Peiwen Ding, Lihua Luo, Xiangning Ding, Chengcheng Sun, Tianming Lan, Sunil Kumar Sahu, Weiying Wu, Yuting Yuan, Wendi Wu, Jiaying Qiu, Yixin Zhu, Qizhen Yue, Yi Jia, Yanan Wei, Qiuyu Qin, Runchu Li, Wandong Zhao, Zhiyuan Lv, Mingyi Pu, Boqiong Lv, Shangchen Yang, Ashley Chang, Xiaofeng Wei, Fengzhen Chen, Tao Yang, Zhenyong Wei, Fan Yang, Peijing Zhang, Guoji Guo, Yuejiao Li, Yan Hua, Huan Liu   +35 more
doaj   +1 more source