Results 101 to 110 of about 8,018,858 (254)

Single event transients monitoring and diagnostic in FPGA

Facta universitatis - series: Electronics and Energetics, 2018
Analysis of single event transients (SETs) generated in field programmable gate arrays (FPGA) under heavy charged particles (HCP) irradiation and SET suppression methods is performed. The circuit for FPGA SET detection is designed for transients generated both inside FPGA and outside at package pin level.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Software modification aided transient error tolerance for embedded systems

, 2013
Commercial off-the-shelf (COTS) components are increasingly being employed in embedded systems due to their high performance at low cost. With emerging reliability requirements, design of these components using traditional hardware redundancy incur large
Kim Sunesen, Sunesen, Kim, Mathew, J., Pradhan, Dhiraj K., Gerard Rauwerda, Sunesen, K., Ioannis Sourdis, Shafik, Rishad Ahmed, Potman, J., Potman, Jordy, Sourdis, Ioannis, Rishad A. Shafik, Shafik, R.A., Rauwerda, G.K., Jimson Mathew, Pradhan, D.K., Dhiraj K. Pradhan, Mathew, Jimson, Rauwerda, Gerard, Jordy Potman, Mathew, J.,, Rauwerda, G.K.,, Sunesen, K.,, Pradhan, D.K.,, Potman, J.,, Sourdis, Ioannis,, Shafik, R.A.,   +26 more
core   +2 more sources

Position dependent measurement of single event transient voltage pulse shapes under heavy ion irradiation

, 2012
A CMOS inverter in 90 nm CMOS bulk technology was exposed to heavy ion radiation (Au-197) at a micro-beam facility. The targeted inverter occupies an area of 6×3 µm².
Zimmermann, Horst, Merk, B., Schweiger, Kurt, Hofbauer, Michael, Dietrich, Horst, Voss, K.O.   +5 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Analysis of Single-Event Transient in Tunneling-Based Ternary CMOS With Gate-All-Around Structure

IEEE Access
In this study, single-event transient (SET) characteristics in tunneling-based ternary complementary MOS device (T-CMOS) with gate-all-around structure (i.e., nanosheet FET) were analyzed for the first time.
Hyeong-Chan Son, Hyunwoo Kim
doaj   +1 more source

The Effect of Deep N+ Well on Single-Event Transient in 65 nm Triple-Well NMOSFET

, 2019
In a triple-well NMOSFET, a deep n+ well (DNW) is buried in the substrate to isolate the substrate noise. The presence of this deep n+ well leads to changes in single-event transient effects compared to bulk NMOSFET.
Pengcheng Huang, Liang Fang, Jizuo Zhang, Shouping Li, Jianjun Chen   +4 more
core   +1 more source

Transient-grating single-shot supercontinuum spectral interferometry (TG-SSSI)

, 2020
We present a technique for the single-shot measurement of the space- and time-resolved spatiotemporal amplitude and phase of an ultrashort laser pulse.
H. M. Milchberg (14384538), S. W. Hancock (14384532), S. Zahedpour (14384535)   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source