Results 11 to 20 of about 69,820 (250)
Advancing Single-Molecule Biophysics: Next-Generation Organic Fluorophores with Tailored Labeling Strategies [PDF]
Chemical & Biomedical ImagingLei Zhang, Dongwen Shen, Jiazhen Yang
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Getting high on Single Molecule Biophysics. [PDF]
Curr Pharm Biotechnol, 2009 Block S.
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iScience, 2021 Summary: Single-molecule localization microscopy (SMLM) reports on protein organization in cells with near-molecular resolution and in combination with stoichiometric labeling enables protein counting.
Tim N. Baldering +8 more
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Frontiers in Molecular Biosciences, 2021 In addition to the canonical double helix form, DNA is known to be extrapolated into several other secondary structural patterns involving themselves in inter- and intramolecular type hydrogen bonding. The secondary structures of nucleic acids go through
Debolina Bandyopadhyay +3 more
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Nature Communications, 2021 Ring ATPase translocases that operate on disordered substrates adopt lockwasher architectures and use a hand-over-hand mechanism. By challenging the dsDNA packaging motor of bacteriophage ϕ29 with hybrid and dsRNA, the authors propose that the motor ...
Juan P. Castillo +4 more
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Surface Modification of Fluorescent Nanodiamonds for Biological Applications
Nanomaterials, 2021 Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility.
Hak-Sung Jung, Keir C. Neuman
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Biological Nanopores for Single‐Molecule Biophysics [PDF]
ChemBioChem, 2009 Financial support is graciously acknowledged from the Chinese Scholarship Council and the MTEM International Studentship scheme (scholarship to L. M), The Royal Society of Chemistry and The Leverhulme Trust. We thank J. Chu of the Ghadiri laboratory (The Scripps Research Institute) for helpful discussions.
Ma, Long +1 more
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Confined environment facilitates stacked conformations in Holliday Junction
Chemical Physics Impact, 2023 Holliday Junction (HJ) is an important intermediate in homologous recombination and is involved in DNA break repair. It is a highly dynamic structure and transitions between two stacked isomers through an intermediate open conformer. However, the insight
Priya Agarwal +2 more
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Topoisomerase VI is a chirally-selective, preferential DNA decatenase
eLife, 2022 DNA topoisomerase VI (topo VI) is a type IIB DNA topoisomerase found predominantly in archaea and some bacteria, but also in plants and algae. Since its discovery, topo VI has been proposed to be a DNA decatenase; however, robust evidence and a mechanism
Shannon J McKie +5 more
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Biophysical nanotools for single-molecule dynamics [PDF]
Biophysical Reviews, 2018 The focus of the cell biology field is now shifting from characterizing cellular activities to organelle and molecular behaviors. This process accompanies the development of new biophysical visualization techniques that offer high spatial and temporal resolutions with ultra-sensitivity and low cell toxicity. They allow the biology research community to
Qian Peter Su, Lining Arnold Ju
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