Results 21 to 30 of about 70,987 (292)

Biological Nanopores for Single‐Molecule Biophysics [PDF]

open access: yesChemBioChem, 2009
Financial support is graciously acknowledged from the Chinese Scholarship Council and the MTEM International Studentship scheme (scholarship to L. M), The Royal Society of Chemistry and The Leverhulme Trust. We thank J. Chu of the Ghadiri laboratory (The Scripps Research Institute) for helpful discussions.
Ma, Long   +1 more
openaire   +2 more sources

Confined environment facilitates stacked conformations in Holliday Junction

open access: yesChemical Physics Impact, 2023
Holliday Junction (HJ) is an important intermediate in homologous recombination and is involved in DNA break repair. It is a highly dynamic structure and transitions between two stacked isomers through an intermediate open conformer. However, the insight
Priya Agarwal   +2 more
doaj   +1 more source

Topoisomerase VI is a chirally-selective, preferential DNA decatenase

open access: yeseLife, 2022
DNA topoisomerase VI (topo VI) is a type IIB DNA topoisomerase found predominantly in archaea and some bacteria, but also in plants and algae. Since its discovery, topo VI has been proposed to be a DNA decatenase; however, robust evidence and a mechanism
Shannon J McKie   +5 more
doaj   +1 more source

Biophysical nanotools for single-molecule dynamics [PDF]

open access: yesBiophysical Reviews, 2018
The focus of the cell biology field is now shifting from characterizing cellular activities to organelle and molecular behaviors. This process accompanies the development of new biophysical visualization techniques that offer high spatial and temporal resolutions with ultra-sensitivity and low cell toxicity. They allow the biology research community to
Qian Peter Su, Lining Arnold Ju
openaire   +2 more sources

General Method to Increase Carboxylic Acid Content on Nanodiamonds

open access: yesMolecules, 2022
Carboxylic acid is a commonly utilized functional group for covalent surface conjugation of carbon nanoparticles that is typically generated by acid oxidation.
Ganesh Shenoy   +11 more
doaj   +1 more source

Magnetic nanoparticle-based solid phase peptide synthesis and the synchronous detection of their biological activity

open access: yesMaterials Today Advances, 2021
The solid-phase peptide synthesis (SPPS) strategy, as the main procedure of peptide manufacturing, has a profound impact on the research of peptides.
D. Luo   +8 more
doaj   +1 more source

An Estimation Algorithm for General Linear Single Particle Tracking Models with Time-Varying Parameters

open access: yesMolecules, 2021
Single Particle Tracking (SPT) is a powerful class of methods for studying the dynamics of biomolecules inside living cells. The techniques reveal the trajectories of individual particles, with a resolution well below the diffraction limit of light, and ...
Boris I. Godoy   +2 more
doaj   +1 more source

Viruses and Tetraspanins: Lessons from Single Molecule Approaches

open access: yesViruses, 2014
Tetraspanins are four-span membrane proteins that are widely distributed in multi-cellular organisms and involved in several infectious diseases. They have the unique property to form a network of protein-protein interaction within the plasma membrane ...
Selma Dahmane   +2 more
doaj   +1 more source

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