Ursolic acid protects the kidneys from the consequences of aging through increasing the expression of SIRT1, SIRT6 and α-Klotho in the mice model [PDF]
World Cancer Research Journal, 2021 Objective: In our previous studies on the anti-aging effects of ursolic acid (UA) on various tissues including skeletal muscle, heart, hypothalamus and pancreas, the protective and anti-aging roles of UA on renal tissue remained elusive.
M. Rezaei, N. Bakhtiari
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Association between The SIRT1 and SIRT3 Levels and Gene Polymorphisms with Infertility in War Zones of Kermanshah Province, Iran: A Case-Control Study [PDF]
International Journal of Fertility and Sterility, 2023 Objective: War toxin, mustard gas, alkylating agent results in male infertility via inducing reactive oxygen species (ROS) production and DNA mutagenesis.
Abolfazl Nasiri +3 more
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Frontiers in Bioscience-Landmark, 2022 SIRT1 was discovered in 1979 but growing interest in this protein occurred only 20 years later when its overexpression was reported to prolong the lifespan of yeast.
Zsuzsanna Nemeth +2 more
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PRIMARY INFERTILITY, OXIDATIVE STRESS AND METFORMIN; IMPACT ON PRIMARY HUMAN GRANULOSA CELL CULTURES
Khyber Medical University Journal, 2021 OBJECTIVE: To observe the effect of metformin on oxidative stress (OS) levels and SIRT1 expression in primary human granulosa cell cultures from infertile females.
Faiza Alam +4 more
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Laminar Shear Stress Protects Against Premature Endothelial Senescence by SIRT1-Dependent Mechanisms [PDF]
운동과학, 2021 s PURPOSE Accumulation of senescent endothelial cells (ECs) and development of vascular aging have been implicated in the etiology of vascular dysfunction and disease.
Ji-Seok Kim +3 more
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Tetrahydrocurcumin protects against sepsis-induced acute kidney injury via the SIRT1 pathway
Renal Failure, 2021 Sepsis-induced acute kidney injury (AKI) continues to be associated with poor outcomes in critical care patients. Previous research has revealed that tetrahydrocurcumin (THC) exerts renoprotective effects in multiple nephritic disorders by modulating ...
Lu Li +6 more
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Aerobic Exercise-Mimetic Effects of Resveratrol on the Prevention of Vascular Endothelial Senescence [PDF]
운동과학, 2023 PURPOSE Regular exercise has been shown to have anti-aging effects on the vascular system by improving endothelial function and diminishing oxidative stress.
Ji-Seok Kim
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Food & Nutrition Research, 2022 Background: Resveratrol, a well-known natural compound and nutrient, activates the deacetylation ability of SIRT1, demonstrating p53-dependent apoptosis functions in many diseases. However, the nascent proteomic fluctuation caused by resveratrol is still
Tian Su +6 more
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Journal of Investigative Surgery, 2022 Background: The activation of alveolar macrophages (AMs) modulated via leucine-rich repeat (NLR) pyrin domain containing 3 (NLRP3) inflammasome activation is key to the progression of renal ischemia/reperfusion (rI/R)-mediated acute lung injury (ALI ...
Zhaohui Liu +6 more
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Luteolin alleviates sepsis-induced cardiac injury by activating SIRT1
陆军军医大学学报, 2022 Objective To explore the effect and mechanism of luteolin (LTN) in sepsis-induced cardiac injury. Methods Caecal ligation perforation (CLP) was used to establish a septic model in mice, and 42 mice were randomly divided into Sham group, CLP group and ...
LIU Bin, LONG Jun, SI Liangyi
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