Results 131 to 140 of about 77,206 (307)

Liraglutide exerts an anti-inflammatory action in obese patients with type 2 diabetes

open access: yesRomanian Journal of Internal Medicine, 2019
Introduction. Liraglutide (L) is the analogue of human glucagon-like peptide 1 which stimulates glucose-dependent insulin secretion and can modify the level of inflammatory biomarkers.
Savchenko Liudmyla G.   +6 more
doaj   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

open access: yesFood Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

SIRT1 gene polymorphisms and risk of lung cancer

open access: yes, 2017
Yanbo Lv, Shuangyan Lin, Fang Peng Department of Pathology, Zhejiang Hospital, Hangzhou City, Zhejiang, China Objective: Lung cancer, which is the leading cause of cancer death worldwide, is influenced by a wide variety of environmental and ...
Peng F, Lv Y, Lin SY
core  

Phosphorylation regulates SIRT1 function.

open access: yes, 2008
BackgroundSIR2 is an NAD(+)-dependent deacetylase [1]-[3] implicated in the regulation of lifespan in species as diverse as yeast [4], worms [5], and flies [6].
Heidi Scrable   +15 more
core   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

open access: yesFood Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng   +5 more
wiley   +1 more source

Inhibition studies of SIRT1 [PDF]

open access: yes, 2013
Thesis (M.A.)--Boston UniversitySilent Information Regulator 2 (Sir2) of Saccharomyces cerevisiae is the progenitor of an ancient family of proteins known as sirtuins.
Bonetti, Kelly
core   +1 more source

Skeletal muscle SIRT1 and the genetics of metabolic health: therapeutic activation by pharmaceuticals and exercise

open access: yes, 2012
Cameron B Williams, Brendon J GurdSchool of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, CanadaAbstract: Silent mating type information regulation 2 homolog 1 (SIRT1) is implicated in the control of skeletal muscle ...
Williams CB, Gurd BJ
core  

Effect of SIRT1 or SIRT1 (H363Y) overexpression on acetylation of p53 in C2C12 myoblasts.

open access: yes, 2015
(A) Protein expression of SIRT1 or SIRT1 (H363Y) in C2C12 myoblasts; (B) acetyl-p53 (K376) in C2C12 myoblasts overexpressing empty vector, SIRT1 or SIRT1 (H363Y ...
Gregory J. Cooney (183923)   +9 more
core   +1 more source

Metabolite Profiles and Antioxidant Activity of Dendrobium catenatum Under Simulated Wild Cultivation

open access: yesFood Safety and Health, EarlyView.
Dendrobium catenatum grown under simulated wild cultivation showed significantly higher flavonoids and stilbenes, leading to enhanced antioxidant activity in both leaves and stems compared to facility‐grown plants. Integrated metabolomics, antioxidant assays, and network pharmacology identified Denbinobin as a key multi‐target antioxidant compound ...
Chuyun Guan   +7 more
wiley   +1 more source

Inhibition of SIRT1 combined with gemcitabine therapy for pancreatic carcinoma

open access: yes, 2013
Dao-Jun Gong,1 Jia-Min Zhang,1 Min Yu,1 Bo Zhuang,1 Qing-Qu Guo21Department of Hepatobiliary-Pancreatic Surgery, Jinhua Hospital of Zhejiang University, Jinhua, People's Republic of China; 2Department of Surgery, Second Affiliated Hospital of ...
Zhang JM   +4 more
core  

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