Results 101 to 110 of about 6,075 (158)

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

, 2008
Sirt7 is a member of the mammalian sirtuin family consisting of 7 genes, Sirt1 to Sirt7, which all share a homology to the founding family member, the yeast Sir2 gene.
Kostin, S., Gajawada, P., Bober, E., Kubin, T., Smolka, C., Vakhrusheva, O., Braun, T., Boettger, T.   +7 more
core  

Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells

Cell Death and Disease
Cisplatin (CDDP) resistance has been established to significantly impact Bladder Cancer (BCa) therapy. On the other hand, the crucial regulatory involvement of SIRT7 and EZH2 in bladder cancer development is well known.
Yudong Cao, Shuo Wang, Jinchao Ma, Mengping Long, Xiuli Ma, Xiao Yang, Yongpeng Ji, Xingxing Tang, Jia Liu, Chen Lin, Yong Yang, Peng Du   +11 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of SIRT7 in Angiogenesis: Insights from Substrate Clues

Angiogenesis, a vital physiological or pathological process regulated by complex molecular networks, is widely implicated in organismal development and the pathogenesis of various diseases.
Meiting Li, Haiying Wang, Jiaxing Wu, Jianyuan Luo, Junjie Ma, Jiaqi Zhang, Liqian Yang, Zhihong Huang, Minghui Liu   +8 more
core   +1 more source

Eriocitrin Attenuates Diabetic Cardiomyopathy by Regulating Copper Homeostasis and Cuproptosis-Associated Pathways via SIRT7/YAP/ATP7A Signalling. [PDF]

Basic Clin Pharmacol Toxicol
Chen L, Mao S, Yu Y, Zhang D, Fan Z.
europepmc   +1 more source

SIRT7 upregulation protects against TKI-induced cardiotoxicity by inhibiting MCU-mediated mitochondrial calcium overload. [PDF]

Front Pharmacol
Gao M, Wang Z, Cheng Z, Qiu S, Wu W, Zhang Z, Yan W, Wang X, Xu Y, Li C.   +9 more
europepmc   +1 more source

SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis

, 2019
The central pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) synchronizes peripheral oscillators to coordinate physiological and behavioural activities throughout the body.
Zhao, B, Guan, Y, Wang, Z, Liu, Z, Pang, Q, Zhang, S, Li, G, Cao, X, Tan, B, Sun, J, Tang, X, Sun, S, Meng, F, Hu, W, Qian, M, Ruan, X, Liu, B, Xu, C   +17 more
core  

Altered Embryonic SIRT6 and SIRT7 Expression Is Associated with Impaired Developmental Competence and Oocyte-Dependent Embryo Quality in Embryos Derived from Subfertile Males. [PDF]

Int J Mol Sci
Kowalczyk A, García MC, Hernández Malagón JÁ, Araujo JP, Žura Žaja I, Pećin M, Đuričić D, Gałęska E, Dobrzański Z, Samardžija M.   +9 more
europepmc   +1 more source

Comparative Structure-Based Analysis of Predicted BZD9L1 Binding Modes Across Human Sirtuins. [PDF]

Int J Mol Sci
Tan YJ, Lee YT, Oon CE, Mancera RL.
europepmc   +1 more source

LncRNA RP11-708J19.2 promotes colorectal cancer progression by binding to SIRT7 <i>via</i> regulating H3K18ac. [PDF]

Eur J Histochem
Ma J, Tian X, Qiu Y, Zhao C, Wang J, Jia R.   +5 more
europepmc   +1 more source

ATAD2 suppresses senescence and SASP via SIRT7-p53/p21 to drive progression and immune evasion in endometrial cancer. [PDF]

Clin Epigenetics
Wang C, Osipova A, Wang Y, Li F, Wang H, Hu J, Chen X.   +6 more
europepmc   +1 more source