Results 221 to 230 of about 74,229 (355)

Sirtuin 1 and Sirtuin 2 Gene Expressions in Colorectal Cancers. [PDF]

J Clin Pract Res
Düzenli T, Doğan D, Barışık NÖ.
europepmc   +1 more source

Sirtuins and Longevity

, 2012
P S Shankar
openalex   +1 more source

Hepato‐Renal Protective Potential of Dimethyl Fumarate in Alloxan‐Induced Diabetic Mice Model by Modulating of Sirt1, Nrf2 and Inflammatory Genes Expressions

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Hepato‐renal protective potential of DMF in alloxan‐induced diabetic mice model. ABSTRACT Aim Despite advances in diabetes treatments, the effects of this disease have not yet been adequately reversed or prevented in patients. Therefore, development of more effective medication‐assisted treatments in this field is needed.
Parisa Saberi‐Hasanabadi, Fatemeh Shaki, Mohammad Karami, Abouzar Bagheri, Mohammad Ranaee, Ramin Ataee   +5 more
wiley   +1 more source

Fat mass and obesity-associated protein downregulation trigger the activation of the sirtuin 1/forkhead box O1 signaling pathway, drive glycolysis, and promote the progression of renal cell carcinoma

Zheng Zhang, Jifeng Zhang, Ren-Zhong Zhang   +2 more
openalex   +1 more source

Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease

Glia, Volume 74, Issue 3, March 2026.
APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar, Yucheng Xiao, Neha Mahajan, Qianyi Luo, Theodore R. Cummins, Adrian L. Oblak, Bruce T. Lamb, Timothy W. Corson, Ashay D. Bhatwadekar   +8 more
wiley   +1 more source

Sirtuins and regulatory miRNAs as epigenetic determinants of empagliflozin-mediated recovery after acute myocardial infarction. [PDF]

Cardiovasc Diabetol
Nowak-Szwed A, Eyileten C, Wicik Z, Ahmadova S, Palatini J, Siller-Matula J, von Lewinski D, Sourij H, Postula M.   +8 more
europepmc   +1 more source

SIRTUIN 1 ACTIVATOR SRT1720 PROTECTS AGAINST ORGAN INJURY INDUCED BY INTESTINAL ISCHEMIA-REPERFUSION

, 2015
Laura W. Hansen, Adam Khader, Weng-Lang Yang, José M. Prince, Jeffrey Nicastro, Gene F. Coppa, Ping Wang   +6 more
openalex   +2 more sources

Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox‐inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved enzymes, an NAD(P)HX dehydratase (NAXD) and an NAD(P)HX epimerase (NAXE).
Myrto Patraskaki, Najmesadat Seyedkatouli, Lisa Schlicker, Marc O. Warmoes, Maria Lorena Cordero‐Maldonado, Ursula Heins‐Marroquin, Carole L. Linster   +6 more
wiley   +1 more source

Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans. [PDF]

Genetics
Chang SM, Franklin LP, Sattar S, Moro CA, DeGennaro MV, LaGanke NG, Hanna-Rose W.   +6 more
europepmc   +1 more source

Update on Sirtuins : is there any clinical relevance?

, 2016
Alfred Grech, Michael Balzan
openalex   +1 more source