Results 221 to 230 of about 87,529 (407)

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control [PDF]

, 2016
Imai, Shin-ichiro
core   +2 more sources

Download the full PDF of Jefferson Surgical Solutions Spring 2009, Volume 4, Number 1. [PDF]

, 2009
Download the full PDF of Jefferson Surgical Solutions Spring 2009, Volume 4, Number ...

core   +1 more source

Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory-entorhinal-amygdaloid axis in Alzheimer´s and Parkinson´s diseases [PDF]

, 2022
Paz Cartas‐Cejudo, Mercedes Lachén‐Montes, Isidró Ferrer, Joaquín Fernández‐Irigoyen, Enrique Santamaría   +4 more
openalex   +1 more source

Environmental modulators of vascular physiology and inflammation

Experimental Physiology, EarlyView.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller   +3 more
wiley   +1 more source

THE SIGNALING PATHWAY OF SRF-SIRTUIN-2 GENE AND MITOCHONDRIAL FUNCTION [PDF]

Xiaomin Zhang, Gohar Azhar, Fathima S. Ameer, Jeanne Y. Wei   +3 more
openalex   +1 more source

Supplementary Figure 6 from Tenovin-D3, a Novel Small-Molecule Inhibitor of Sirtuin SirT2, Increases p21 (<i>CDKN1A</i>) Expression in a p53-Independent Manner

, 2023
Anna R. McCarthy, Marijke C.C. Sachweh, Maureen Higgins, Johanna Campbell, Catherine J. Drummond, Ingeborg M.M. van Leeuwen, Lisa Pirrie, Marcus J.G.W. Ladds, Nicholas J. Westwood, Sonia Laı́n   +9 more
openalex   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Enviromimetics: From exercise mimetics to cognitomimetics in the quest for enhanced brain health and cognition

The Journal of Physiology, EarlyView.
Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley   +1 more source

Additional file 13 of Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet

, 2021
Laura A. Cox, Jeannie Chan, Prahlad Rao, Zeeshan Hamid, Jeremy P. Glenn, Avinash Jadhav, Vivek Das, Genesio M. Karere, Ellen E. Quillen, Kylie Kavanagh, Michael Olivier   +10 more
openalex   +1 more source