Results 231 to 240 of about 84,834 (402)

Adenosine mimetics as inhibitors of NAD + -dependent histone deacetylases - from kinase to sirtuin inhibition [PDF]

, 2006
Johannes Trapp Anne Jochum Rene Meier Laura Saunders Brett Marshall Conrad Kunick Eric Verdin Peter…
openalex  

Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta‐Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify adverse outcomes and factors associated with diabetes mellitus among children and youths in East Africa. Design This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.
Chalie Marew Tiruneh, Marilyn Cruickshank, Muhammad Chutiyami, Lin Perry   +3 more
wiley   +1 more source

Dysregulation of lncRNA OIP5‐AS1 participants in the progression of diabetic retinopathy and affects the proliferation in retinal vascular endothelial cell

Journal of Diabetes Investigation, EarlyView.
OIP5‐AS1 was down‐regulated in T2DM‐DR patients and regulated cellular functions via targeting miR‐181a‐5p. ABSTRACT Aims This study was to ascertain the clinical performance of OIP5‐AS1 in diabetic retinopathy (DR) and its molecular mechanism in the disease progression. Materials and Methods Subjects included 85 healthy controls, 79 patients with type
Ziwen Yin, Jingyun Dong, Yachao Meng, Zhiqiang Yang, Chunhong Zhao, Qiuyun Wu   +5 more
wiley   +1 more source

Mammalian Sirtuin 1 Is Involved in the Protective Action of Dietary Saturated Fat against Alcoholic Fatty Liver in Mice

, 2008
Min You, Qi Cao, Xiaomei Liang, Joanne M. Ajmo, Gene C. Ness   +4 more
openalex   +1 more source

The Central Sirtuin 1/p53 Pathway Is Essential for the Orexigenic Action of Ghrelin [PDF]

, 2011
D Velasquez, Gloria Martínez, Amparo Romero, María J. Vázquez, Kátia Da Boit, Iria G. Dopeso‐Reyes, Miguel López, Anxo Vidal, Rubén Nogueiras, Carlos Diéguez   +9 more
openalex   +1 more source

Complex Interplay Between Obesity and BRCA1/2‐Associated Breast Cancer: An Overview

Obesity Reviews, EarlyView.
ABSTRACT The steadily increasing prevalence of obesity and its association with a growing number of malignancies, including breast cancer, has made this disease spectrum an urgent and critical public health priority, demanding immediate attention and comprehensive action.
Cinzia Giordano, Marianna Puzzo, Rocco Malivindi, Debora Cristofaro, Luca Gelsomino, Daniela Bonofiglio, Carlo Capalbo, Sebastiano Andò, Ines Barone, Stefania Catalano   +9 more
wiley   +1 more source

Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette, Chloé Ilbert, Sébastien Aimé, Hoai‐Nam Truong, Marielle Adrian, Stéphane Bourque   +5 more
wiley   +1 more source

Elevated Sirtuin 1 Levels in Patients with Chronic Kidney Disease, Including on Peritoneal Dialysis: Associations with Cardiovascular Risk and Peritoneal Fibrosis. [PDF]

Int J Mol Sci
Bielach-Bazyluk A, Czajkowska K, Koc-Zorawska E, Hryszko T, Zbroch E.   +4 more
europepmc   +1 more source

Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

Critical reviews in biochemistry and molecular biology, 2018
Surinder Kumar, D. Lombard
semanticscholar   +1 more source

Sirtuins at the Breaking Point: SIRT6 in DNA Repair

, 2009
David B. Lombard
openalex   +1 more source