Results 171 to 180 of about 17,907 (258)

Flow Cytometry Role in Unlocking New Frontiers for Nanomedicine Applications of Plant‐Derived Vesicles

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound vesicles released by any cell type under both physiological and pathological conditions. They carry a wide array of bioactive molecules, including microRNAs (miRNAs), lipids, proteins and other small biomolecules, and therefore play a key role in intercellular communication by ...
Tamer Esmail, Sabino Porro, Francesca D'Ascanio, Domenico De Bellis, Arianna Aquilini‐Mummolo, Giulia Colasante, Pasquale Simeone, Ayesha Younas, Marwa Balaha, Mariagiulia Filoso, Luana D'Onofrio, Melania Dovizio, Eleonora Aruffo, Piero Di Carlo, Lorenzo Secondi, Federica Flamminii, Tiziana Pietrangelo, Chiara Porro, Patrizia Ballerini, Angelo Cichelli, Paola Lanuti   +20 more
wiley   +1 more source

Sirtuins and tumor immunity: mechanistic insights, immunotherapy prospects, and therapeutic horizons. [PDF]

Front Immunol
Gu J, Liu S, Xiao W, Qu W.
europepmc   +1 more source

Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox‐inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved enzymes, an NAD(P)HX dehydratase (NAXD) and an NAD(P)HX epimerase (NAXE).
Myrto Patraskaki, Najmesadat Seyedkatouli, Lisa Schlicker, Marc O. Warmoes, Maria Lorena Cordero‐Maldonado, Ursula Heins‐Marroquin, Carole L. Linster   +6 more
wiley   +1 more source

Tuned by time: the role of circadian rhythms in metabolic energy sensing and chronotherapy. [PDF]

Ann Med
Thanuskodi Rajakumar A, Kodiveri Muthukaliannan G.   +1 more
europepmc   +1 more source

NAD+ Enhanced on Hearing Recovery in Sudden Sensorineural Hearing Loss: Randomized Controlled Trial

The Laryngoscope, Volume 136, Issue 3, Page 1204-1214, March 2026.
This 2‐year, single‐center, double‐blind study with a small sample size compared NAD+ and control groups in a randomized controlled trial for sudden sensorineural hearing loss (SSNHL). Results showed that NAD+ led to better hearing improvement from 7 days to 3 months and a shorter average recovery time compared to the control group.
Minqian Gao, Yingting Guan, Xuejing Yue, Hao Bao, Qianwen Li, Yiqing Zheng, Yongkang Ou, Haidi Yang   +7 more
wiley   +1 more source

Managing the negative regulation of Sirtuins in a murine model of premature ovarian failure: focusing on the key roles of antioxidants. [PDF]

J Ovarian Res
Nasab SE, Shahhoseini M, Tavana S.
europepmc   +1 more source

Targeting Delivery of Cyanidin‐Loaded With Ti3C2 Nanosheets for Alleviating Vascular Calcification in Chronic Kidney Disease

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Vascular calcification significantly elevates cardiovascular risk in CKD patients, yet no effective therapies exist to halt its progression. We developed a dual targeting nanoplatform Ti3C2/RANKL/OCN/Cyanidin (TROC) for the targeted delivery of cyanidin against vascular calcification.
Li Yin, Xiaoge Zhang, Huanji Zhang, Changming Xie, Zhengzhipeng Zhang, Dong Wang, Yuning Liu, Bing Dong, Leilei Shi, Jie Liu, Hui Huang   +10 more
wiley   +1 more source

Mitochondrial sirtuins, key regulators of aging. [PDF]

Life Med
Ji Z, Liu GH, Qu J.
europepmc   +1 more source

Cerebrospinal Fluid Genetics Enhance Risk Stratification in Bipolar Disorder

MedComm, Volume 7, Issue 3, March 2026.
This study introduced a novel genetic proxy strategy that connects the CSF biomarkers with the clinical applications in BD research. First, it delineated a genetically anchored CSF biomarker network. Second, it demonstrated the clinical utility of multimodal PRS. Finally, it provided a scalable framework for risk stratification. These insights pave the
Yu Feng, Xiaonan Guo, Peng Huang, Xiaolong Ji, Ningning Jia, Sheng Yang, Shaohua Hu   +6 more
wiley   +1 more source

The Role of Sirtuins in Bone Repair From the Perspective of Glucose Metabolism. [PDF]

Int J Gen Med
Ding Y, Gao Y, Sun J, Cai Z.
europepmc   +1 more source