Results 181 to 190 of about 22,350 (290)

Retraction: Differential expression of sirtuins in the aging rat brain. [PDF]

Front Cell Neurosci
Frontiers Editorial Office.
europepmc   +1 more source

FGF21/sirtuin 1 axis mediates the cardioprotective effects of high‐intensity interval training against doxorubicin‐induced cardiotoxicity by reducing inflammatory and oxidative stress

Experimental Physiology, EarlyView.
Abstract Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent, but its clinical use is limited by cumulative cardiotoxicity. Exercise, particularly high‐intensity interval training (HIIT), has emerged as an effective non‐pharmacological strategy to counteract chemotherapy‐induced cardiac injury.
Mahdiyeh Farahani, Abbas Ali Gaeini, Alireza Ghardashi Afousi, Mahboobeh Borjian Fard   +3 more
wiley   +1 more source

Toxoplasma gondii SIR2A Promotes Tachyzoite Invasion via Lysine Deacetylase Activity. [PDF]

FASEB J
Wu Y, Liu X, Tian X, Xie Y, Wu Y, Zheng X, Hu X, Hua Q, Zhao W, Mou Y, Tan F.   +10 more
europepmc   +1 more source

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

Experimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

Comparative Structure-Based Analysis of Predicted BZD9L1 Binding Modes Across Human Sirtuins. [PDF]

Int J Mol Sci
Tan YJ, Lee YT, Oon CE, Mancera RL.
europepmc   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

Experimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera, Jose Lozano‐Meca, Miguel López‐Moreno, Edgar Simón Sancho‐Haro, Mario Muñoz‐López, Eneko Baz‐Valle, José Francisco López‐Gil, Rodrigo Yáñez‐Sepúlveda, Vicente Javier Clemente‐Suárez   +8 more
wiley   +1 more source

<i>Sechium edule</i> var. <i>nigrum spinosum</i> (Chayote) Increases the mRNA Expression of Genes Encoding Sirtuins in Older Adults with Type 2 Diabetes Mellitus. [PDF]

Molecules
Gavia-García G, Hernández-Álvarez D, Arista-Ugalde TL, Aguiñiga-Sánchez I, Santiago-Osorio E, Cadena-Iñiguez J, Rosado-Pérez J, Mendoza-Núñez VM.   +7 more
europepmc   +1 more source

SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing [PDF]

, 2015
Jenkins, Gail, Wakeling, Luisa, Gail Jenkins, Escolme, Suzanne, Laura J Ions, Madhurima Dey, Tianhong Su, Dianne Ford, Wainwright, Linda, Simon J Cockell, Jill A McKay, Linda J Wainwright, Luisa A Wakeling, Ions, Laura, Su, Tianhong, Hampton, Emily, McKay, Jill, Suzanne M Escolme, Cockell, Simon, Emily V Hampton, Ford, Dianne, Dey, Madhurima   +21 more
core   +1 more source

Sirtuin signalling governs calcium homeostasis and mitochondrial function in metabolic syndrome cardiomyocytes

Experimental Physiology, EarlyView.
Abstract Metabolic syndrome (MetS) is a major contributor to cardiovascular disease and is characterized by impaired Ca2+ handling and mitochondrial dysfunction in cardiomyocytes. However, the upstream mechanisms linking metabolic stress to these alterations remain incompletely defined.
Firat Akat, Leila Aryan, Suatnur Şık, Erkan Tuncay   +3 more
wiley   +1 more source

Subtype-specific sirtuin expression signatures link mitochondrial-epigenetic networks to breast cancer survival. [PDF]

Geroscience
Ungvari Z, Menyhárt O, Ocana A, Lehoczki A, Fekete M, Bianchini G, Győrffy B.   +6 more
europepmc   +1 more source