Results 181 to 190 of about 30,210 (302)

The deacetylase Sir2 is the primary sensor driving transcriptional changes in response to low NAD+ in the yeast Kluyveromyces lactis. [PDF]

Genetics
Acharjee M, Humphrey K, Lactaoen V, Karageorgiou C, Liu B, Gokcumen O, Rusche LN.   +6 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Potential 14-3-3 binding sites in sirtuins reveal extended phosphosite-recognition modes. [PDF]

Acta Crystallogr F Struct Biol Commun
Weyand M, Quast L, Steegborn C.
europepmc   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans. [PDF]

Genetics
Chang SM, Franklin LP, Sattar S, Moro CA, DeGennaro MV, LaGanke NG, Hanna-Rose W.   +6 more
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR‐217/SIRT1/Nrf2 pathway

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
These findings indicate that urinary exosomal miR‐217 promotes podocyte ferroptosis and DKD progression via suppression of the SIRT1/Nrf2 pathway, suggesting a potential therapeutic target for DKD. Abstract Urinary exosomal microRNAs (miRNAs) mediate intercellular communication in diabetic kidney disease (DKD), a leading contributor to end‐stage renal ...
Xin Du, Yubo Jiang, Hongbin Guo, Haiying Zhang, Shaoqing Wang, Hao Deng, Xinyi Huang, Xiu Li   +7 more
wiley   +1 more source

Evaluation of Molecular Responses and Longevity Markers in <i>Acheta domesticus</i> Following Combined Resveratrol and Nanodiamond Exposure. [PDF]

Int J Mol Sci
Ziętara-Krzyk P, Flasz B, Augustyniak M.   +2 more
europepmc   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Oxidative Stress, Mitochondrial Homeostasis, and Sirtuins in Atrial Fibrillation. [PDF]

Int J Mol Sci
Krekora J, Pawlowska E, Derwich M, Drożdż J, Blasiak J.   +4 more
europepmc   +1 more source