Results 201 to 210 of about 30,210 (302)

Effect of Anthocyanin‐Rich New Zealand Blackcurrant on Tumour Necrosis Factor‐α–Induced Plasminogen Activator Inhibitor‐1 Release in Airway Epithelial Cells: A Preliminary Study

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz, Ayesha Zahid, Rati Jani, Lada Vugic, Indu Singh, Natalie Shilton   +5 more
wiley   +1 more source

Oxidative Stress, Mitochondrial Quality Control, Autophagy, and Sirtuins in Heart Failure. [PDF]

Int J Mol Sci
Krekora J, Derwich M, Drożdż J, Pawlowska E, Blasiak J.   +4 more
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

The crosstalk between MicroRNAs and sirtuins: a bit unexpected therapeutic target for cardiovascular diseases. [PDF]

Eur J Med Res
Kamvar R, Barjasteh AH, Omouri-Kharashtomi M, Roumiani PH, Beheshtirooy A, Adib-Hajbagheri P, Rezaei P, Shokraei R, Pourhanifeh MH.   +8 more
europepmc   +1 more source

Sirtuin regulation of NLRP3 [PDF]

Nature Immunology, 2020
openaire   +2 more sources

Sphingosine‐1‐Phosphate Promotes FOS Activation in Osteosarcoma Under Tumor Acidosis

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The tumor microenvironment in solid tumors is characterized by extracellular acidosis, which promotes cancer aggressiveness. In osteosarcoma, the most common primary bone cancer, a highly acidic tumor microenvironment is associated with metastasis and poor prognosis, partly due to metabolic rewiring, including changes in lipid pathways ...
Nicolò Bozzini, Margherita Cortini, Alberto Righi, Agamemnon E. Grigoriadis, Michael Dack, Elizabeta Ilieva, Federica Torricelli, Veronica Manicardi, Nicola Baldini, Sofia Avnet   +9 more
wiley   +1 more source

Correction: Zgutka et al. Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus. <i>Pharmaceuticals</i> 2025, <i>18</i>, 41. [PDF]

Pharmaceuticals (Basel)
Zgutka K, Tkacz M, Grabowska M, Mikołajek-Bedner W, Tarnowski M.   +4 more
europepmc   +1 more source

Don't Cut the Cord: Why Umbilical Cord Blood Still Deserves a Place in Transplantation

International Journal of Immunogenetics, Volume 53, Issue 3, Page 229-239, June 2026.
ABSTRACT The use of umbilical cord blood (UCB) as a stem cell source in haematopoietic stem cell transplant (HSCT) has greatly declined in recent years. It has largely been replaced by mismatched unrelated and family donors, facilitated by advances in transplant technologies, including post‐transplant cyclophosphamide to prevent graft‐versus‐host ...
Jenna Nunn, Kay Poulton, Robert Wynn
wiley   +1 more source

Plasma levels of sirtuin 1 and sirtuin 2 in ascending aortic aneurysm patients - a comparative study. [PDF]

Cardiol J
Krekora J, Matuszewska-Brycht O, Fryczak J, Stępiński P, Krejca M, Siejka A, Kaczmarek D, Merks P, Drożdż J.   +8 more
europepmc   +1 more source

Facile Synthesis of H‐L‐Photo‐Lysine and Its Genetic Incorporation Into Proteins

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
An efficient synthesis of a diazirine‐based noncanonical amino acid (ncAA), photo‐lysine (photoK), is reported, and its genetic incorporation into green fluorescent protein (GFP) is demonstrated. PhotoK‐enabled crosslinking is used to capture substrates and interaction partners of SIRT6 in vitro, in Escherichia coli, and in HEK293 cell lysates ...
Abu Hamza, Chiranjeev Sharma, Yana Cen
wiley   +1 more source