Advances in microbial degradation of skatole: A review [PDF]
Current Research in Microbial SciencesIn recent years, foul odors have led to widespread public complaints and have become a prominent issue in the field of environmental protection. Skatole, as one of the important components of foul odors, is a decomposition product of tryptophan in the ...
Bingjie Xu +6 more
doaj +5 more sources
Ecotoxicology and Environmental Safety, 2023 Skatole is a typical malodor compound in animal wastes. Several skatole-degrading bacterial strains have been obtained, whereas the molecular response of strains to skatole stress has not been well elucidated.
Qiao
exaly +4 more sources
Skatole Alleviates Osteoarthritis by Reprogramming Macrophage Polarization and Protecting Chondrocytes [PDF]
ResearchOsteoarthritis (OA) is the most prevalent joint disease, yet effective disease-modifying OA drugs (DMOADs) remain elusive. Targeting macrophage polarization has emerged as a promising avenue for OA treatment.
Weiyun Wang +17 more
doaj +3 more sources
Molecular Analysis of Indole and Skatole Decomposition Metabolism in Acinetobacter piscicola p38 Utilizing Biochemical and Omics Approaches [PDF]
MicroorganismsIndole and skatole (3-methylindole, C9H9N) are common nitrogen-containing heterocyclic pollutants found in waste, wastewater treatment plants, and public restrooms and are the most notorious compounds in animal feces.
Zhonghao Wang +11 more
doaj +3 more sources
Molecular Mechanisms of Skatole-Induced Inflammatory Responses in Intestinal Epithelial Caco-2 Cells: Implications for Colorectal Cancer and Inflammatory Bowel Disease [PDF]
CellsInflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), in intestinal epithelial cells significantly contribute to inflammatory bowel disease (IBD) and colorectal cancer (CRC).
Katsunori Ishii +5 more
doaj +3 more sources
Nutritional Influences on Skatole Formation and Skatole Metabolism in the Pig
Animals, 2012 Skatole is a tryptophan (TRP) metabolite with fecal odor. Together with the testicular steroid androstenone it is regarded as a main determinant of boar taint, even if elevated concentrations of skatole occur occasionally in gilts and barrows.
Raffael Wesoly, Ulrike Weiler
exaly +5 more sources
Influence of Different Plant Extracts on CYP-Mediated Skatole and Indole Degradation in Pigs [PDF]
AnimalsOne of the primary substances responsible for the unpleasant odor in boar meat is skatole. Enzymes belonging to the cytochrome P450 (CYP) family play a pivotal role in the hepatic clearance of skatole.
Philipp Marro +2 more
doaj +3 more sources
Nature Communications, 2018 Skatole is a bacterial metabolite responsible for boar taint and the objectionable smell of manure. Here, the authors elucidate the final step of skatole biosynthesis, describing the discovery and biochemical characterization of the enzyme catalysing the
Dazhi Liu +2 more
exaly +3 more sources
Screening of skatole-degrading bacteria and control of human fecal odor by compound bacteria
Annals of Microbiology, 2023 Purpose The biodegradation of skatole was used as a starting point in this study, and existing strains of degrading NH3 and H2S in the laboratory were combined to create a composite deodorant.
Jiangyu Ye, Qian Fu
doaj +2 more sources
Animal Nutrition, 2023 Skatole, a strong fecal odor substance, is generated through microbial degradation of tryptophan in the animal hindgut. It easily accumulates in adipose tissue and affects meat quality.
Yuqing Sun +9 more
doaj +2 more sources