Results 31 to 40 of about 68,097 (255)
Disease-Induced Skeletal Muscle Atrophy and Fatigue [PDF]
Medicine & Science in Sports & Exercise, 2016 Numerous health problems, including acute critical illness, cancer, diseases associated with chronic inflammation, and neurological disorders, often result in skeletal muscle weakness and fatigue. Disease-related muscle atrophy and fatigue is an important clinical problem because acquired skeletal muscle weakness can increase the duration of ...
Powers, Scott K. +4 more
openaire +2 more sources
Cells, 2021 Loss of myofibers during muscle atrophy affects functional capacity and quality of life. Dexamethasone, an inducer of rapid atrophy of skeletal myofibers, has been studied as a glucocorticoid receptor in muscle atrophy or motor neurodegeneration. In this
Bomi Ryu +3 more
doaj +1 more source
Skeletal muscle inflammation and atrophy in heart failure [PDF]
Heart Failure Reviews, 2017 Heart failure represents a systemic disease with profound effects on multiple peripheral tissues including skeletal muscle. Within the context of heart failure, perturbations in skeletal muscle physiology, structure, and function strongly contribute to exercise intolerance and the morbidity of this devastating disease.
Kory J, Lavine, Oscar L, Sierra
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Kidney & Blood Pressure Research, 2023 Introduction:Protein-energy waste (PEW) is a common complication in patients with chronic kidney disease (CKD), among which skeletal muscle atrophy is one of the most important clinical features of PEW.
Ting Zhou +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Component identification of buyang huanwu decoction and the effect of main components on preventing muscle atrophy [PDF]
Kafkas Universitesi Veteriner Fakültesi DergisiBuyang Huanwu Dcoction (BYHWD) is a traditional Chinese medicine that has been widely used for the clinical treatment of skeletal muscle atrophy which is a common complication after motor neuron injury and seriously affects the recovery of skeletal ...
Lan ZHOU +5 more
doaj +1 more source
TWEAK and TRAF6 regulate skeletal muscle atrophy [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2012 To discuss the roles and mechanisms of action of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and tumor necrosis factor receptor-associated factor 6 (TRAF6) in skeletal muscle atrophy.Proinflammatory cytokines are known to mediate muscle atrophy in many chronic disease states.
Ashok, Kumar +2 more
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Frontiers in Pharmacology, 2022 Skeletal muscle atrophy is a common and serious complication of chronic kidney disease (CKD). Oxidative stress and mitochondrial dysfunction are involved in the pathogenesis of muscle atrophy.
Qiang Li +9 more
doaj +1 more source