Denervation does not induce muscle atrophy through oxidative stress
European Journal of Translational Myology, 2017 Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Eva Pigna +10 more
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Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine
Medical Sciences, 2018 Skeletal muscle comprises approximately 40% of the total body mass. Preserving muscle health and function is essential for the entire body in order to counteract chronic diseases such as type II diabetes, cardiovascular diseases, and cancer.
Manuela Cervelli +5 more
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PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior [PDF]
, 2014 The benefits of exercise on wellbeing have been known to mankind for thousands of years, yet the underlying mechanisms of exercise have been explained only relatively recently.
Dinulović, Ivana
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The role of NLRP3 inflammasome in inflammation-related skeletal muscle atrophy
Frontiers in Immunology, 2022 Skeletal muscle atrophy is a common complication in survivors of sepsis, which affects the respiratory and motor functions of patients, thus severely impacting their quality of life and long-term survival.
Yukun Liu +6 more
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UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. [PDF]
, 2019 We aimed to investigate a novel and uncharacterised E3 ubiquitin ligase in skeletal muscle atrophy, recovery from atrophy/injury, anabolism and hypertrophy.
core +1 more source
Characterisation and expression analysis of cathepsins and ubiquitin-proteasome genes in gilthead sea bream (Sparus aurata) skeletal muscle [PDF]
, 2015 This work was supported by funds from the MICINN (AGL2009-12427 and AGL2010-17324), the Catalonian Government (2009SGR-00402) and the “Xarxa de Referència d’R + D + I en Aqüicultura” and, the European Union through the project LIFECYCLE (FP7-222719 ...
Joaquim Gutiérrez +14 more
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Disease-Induced Skeletal Muscle Atrophy and Fatigue [PDF]
Medicine & Science in Sports & Exercise, 2016 Numerous health problems, including acute critical illness, cancer, diseases associated with chronic inflammation, and neurological disorders, often result in skeletal muscle weakness and fatigue. Disease-related muscle atrophy and fatigue is an important clinical problem because acquired skeletal muscle weakness can increase the duration of ...
Powers, Scott K. +4 more
openaire +2 more sources
The role of mTOR complex 1 in skeletal muscle [PDF]
, 2012 An important factor in energy and nutrient pathways is the mammalian target of rapamycin complex 1 (mTORC1). The multiprotein complex, with the central component mTOR, regulates cell growth and survival.
Romanino, Klaas Emilio Antonius Anna
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Cells, 2021 Loss of myofibers during muscle atrophy affects functional capacity and quality of life. Dexamethasone, an inducer of rapid atrophy of skeletal myofibers, has been studied as a glucocorticoid receptor in muscle atrophy or motor neurodegeneration. In this
Bomi Ryu +3 more
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TWEAK and TRAF6 regulate skeletal muscle atrophy [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2012 To discuss the roles and mechanisms of action of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and tumor necrosis factor receptor-associated factor 6 (TRAF6) in skeletal muscle atrophy.Proinflammatory cytokines are known to mediate muscle atrophy in many chronic disease states.
Ashok, Kumar +2 more
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