Results 61 to 70 of about 1,205,857 (255)

Resistance exercise exacerbates muscle atrophy of skeletal muscle-specific Beclin1 conditioned knockout (cKO) mice

Advanced Exercise and Health Science
The autophagy-lysosome pathway is the major route for protein and organelle clearance, and the functional status of autophagy plays an important role in the performance of skeletal muscle.
Zhengzhong Zeng, Hu Zhang, Jiling Liang, Jun Lv, Liangwen Wu, Ning Chen   +5 more
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Soft Actuators Integrated with Control and Power Units: Approaching Wireless Autonomous Soft Robots

Advanced Robotics Research, EarlyView.
Soft robots exhibit significant development potential in various applications. However, there are still key technical challenges regarding material improvement, structure design and components integration. This review focuses on the development and challenge of soft actuators, power components, and control components in untethered intelligent soft ...
Renwu Shi, Feifei Pan, Xiaobin Ji
wiley   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force

, 2019
Background: Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance.
Cheng, Arthur J.,, Chaillou, Thomas,, Martínez-Redondo, Vicente,, Izadi, Manizheh,, Porsmyr-Palmertz, Margareta,, Ruas, Jorge L,, Lanner, Johanna T.,, Hansson, Alicia,, Cervenka, Igor,, Agudelo, Leandro Z.,, Nair, K. Sreekumaran,, Estall, Jennifer L.,, Ferreira, Duarte M. S.,, Robinson, Matthew M.,, Valente-Silva, Paula,, Correia, Jorge C.,, Pettersson-Klein, Amanda T.,   +16 more
core   +1 more source

Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways [PDF]

, 2014
Maintenance of skeletal muscle is essential for health and survival. There are marked losses of skeletal muscle mass as well as strength and physiological function under conditions of low mechanical load, such as space flight, as well as ground based ...
Brooks, Naomi, Myburgh, Kathryn H, Naomi E. Brooks, Kathryn H. Myburgh   +3 more
core   +1 more source

Role of astaxanthin supplementation in prevention of disuse muscle atrophy: a review

Journal of Physical Fitness and Sports Medicine, 2019
Skeletal muscle atrophy is known to occur in various conditions, and is commonly the result of prolonged disuse of the muscle. However, no therapeutic treatment to date has been shown to completely prevent this problem.
Toshinori Yoshihara, Takao Sugiura, Tsubasa Shibaguchi, Hisashi Naito   +3 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source